Flow cytometry analysis of human PBMCs using CXCR5/CD185 Rabbit mAb (ARC62172) clearly classified positive and negative cells. The effects of ABclonal and vendor B are similar.
This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.