产品和服务 / 产品类型 / ELISA试剂盒 / ELISA 抗体对
This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
No significant cross-reactivity or interference was observed.
Placed at 37°C for 7 days, the stability of the standard curve all conform to CV <10%.
* This package insert must be read in its entirety before using this product.
Human IL-15 Sandwich Immunoassay
| Recommended Concentration | Sample | ||
|---|---|---|---|
| ELISA | Capture | 2-8 μg/mL | Rabbit anti-Human IL-15 mAb (Cat. No. RMK0671) |
| Detection | 0.0125-0.05 μg/mL | Rabbit anti-Human IL-15 mAb (Cat. No. RMK0672) | |
| Standard | 3.91-250 pg/mL | Recombinant Human IL-15 Protein (Cat. No. RP01236) |
The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported.
