
产品和服务 / 产品类型 / ELISA试剂盒 / ELISA 抗体对
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Human Thrombopoietin/Tpo Sandwich Immunoassay
| Recommended Concentration | Sample | ||
|---|---|---|---|
| ELISA | Capture | 0.5-2 μg/mL | Rabbit anti-Human Thrombopoietin/Tpo mAb(Cat. No. RMK0588) |
| Detection | 0.034-0.134 μg/mL | Rabbit anti-Human Thrombopoietin/Tpo mAb(Cat. No. RMK0589) | |
| Standard | 4.1-1000 pg/mL | Recombinant Human Thrombopoietin/Tpo Protein (Cat. No.RP00174) |
Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent.