CD205 is a 210-kDa type C lectin transmembrane protein, also known as DEC-205. It belongs to the macrophage mannose receptor family and is highly expressed in dendritic cells and thymic epithelial cells. Unlike murine CD205, human CD205 is also expressed at low levels on T cells, B cells, NK cells, and monocytes. CD205 functions as an endocytic receptor involved in antigen uptake/processing and the clearance of apoptotic cells.
