Recombinant protein (or fragment).This information is considered to be commercially sensitive.
克隆号
ARC55248
产品形式
Liquid
偶联物
APC. Ex:650nm. Em:660nm.
克隆号
ARC55248
产品形式
Liquid
偶联物
APC. Ex:650nm. Em:660nm.
细胞定位
Cell membrane, Secreted, Single-pass type I membrane protein.
存储缓冲液
Store at 2-8℃. Avoid freeze. Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Flow cytometry analysis of human PBMC using APC Rabbit anti-Human/Monkey CD8a mAb (A24799) at 1:20 dilution. clearly classified positive and negative cells.
Flow cytometry analysis of human PBMCs using CD8A Rabbit mAb (ARC55248) clearly classified positive and negative cells. The effect was better than that of vendor B.
Flow cytometry analysis of human PBMCs using ABflo® 594 Rabbit anti-Human CD62L/L-Selectin mAb (A24632), PE Mouse anti-Human CD3 mAb (A22795), ABflo® 488 Rabbit anti-Human/Monkey CD4 mAb (A22773), APC Rabbit anti-Human/Monkey CD8a mAb (A24799) and ABflo® 594 Rabbit anti-Human CD38 mAb (A24366) clearly classified positive and negative cells.
Publishing research using A24799? Please let us know so that we can cite the reference in this datasheet.
背景信息
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.
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