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Rabbit anti-Human IL-13 mAb (RMK0566)

No significant cross-reactivity or interference was observed.

This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

Placed at 37°C for 7 days, the stability of the standard curve all conform to CV <10%.

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货号: RMK0566
价 格:  2100.00
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详细信息

RMK0566
Rabbit anti-Human IL-13 mAb
样本类型
Supplied as a 0.2μm filtered solution in PBS with 0.05% Proclin300, PH 7.4.
检测物种
Rabbit
反应时间
Human
检测范围
Recombinant Human IL-13 protein
组分
Secreted,cytoplasm,external side of plasma membrane,extracellular region,extracellular space.
储存条件
Store at -20℃
安全说明
/
For research purposes only. Not for therapeutic or diagnostic purposes in humans or animals.

* This package insert must be read in its entirety before using this product.

背景信息

This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.