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Rabbit Anti-Human IFN-alpha mAb (RMK0519)

This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

Recognizes the natural and recombinant human IFN-α subtypes listed below: IFN-alpha 2、IFN-alpha 1、IFN-alpha 2b、IFN-alpha 4、IFN-alpha 6 No significant cross-reactivity or interference with IFN beta 、IFN gamma.

Placed at 37°C for 7 days, the stability of the standard curve all conform to CV <10%.

This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

All(4)|
货号: RMK0519
促销价:   ¥2100
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详细信息

产品名称
Rabbit Anti-Human IFN-alpha mAb
货号
RMK0519
免疫原
Recombinant Human IFN-alpha protein
纯化方式
Affinity purification
同种型
Rabbit IgG
存储溶液
Supplied as a 0.2μm filtered solution in PBS with 0.05% Proclin300, PH 7.4.
CrossReactivity
/
存储条件
Store at -20℃.Avoid repeated freeze-thaw cycles.

* This package insert must be read in its entirety before using this product.

应用

Human IFN-alpha Sandwich Immunoassay

  Recommended
Concentration
Sample
ELISACapture1-4ug/mLRabbit anti-Human IFN-alpha mAb(Cat. No.RMK0518)
Detection0.033-0.133ug/mLRabbit anti-Human IFN-alpha mAb(Cat. No.RMK0519)
Standard0.033-0.133ug/mLRecombinant Human IFN-alpha Protein
CLIACapture1-4ug/mLRabbit anti-Human IFN-alpha mAb(Cat. No.RMK0518)
Detection0.5-2ug/mLRabbit anti-Human IFN-alpha mAb(Cat. No.RMK0519)
Standard2.5-2000pg/mLRecombinant Human IFN-alpha Protein

背景信息

This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. The encoded protein is effective in reducing the symptoms and duration of the common cold and in treating many types of cancer, including some hematological malignancies and solid tumors. A deficiency of type I interferon in the blood is thought to be a hallmark of severe COVID-19 and may provide a rationale for a combined therapeutic approach.