产品和服务 / 产品类型 / ELISA试剂盒 / ELISA 抗体对
This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
* This package insert must be read in its entirety before using this product.
Human CD177 Sandwich Immunoassay
| Recommended Concentration | Sample | ||
|---|---|---|---|
| Multiplex | Capture | 3-20 μg/mL | Rabbit anti-Human CD177 mAb (Cat. No. RMK0447) |
| Detection | 0.017-2 μg/mL | Rabbit anti-Human CD177 mAb (Cat. No. RMK0448) | |
| Standard | 6.86-5000 pg/mL | Recombinant Human CD177 Protein |
This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.
