产品和服务 / 产品类型 / ELISA试剂盒 / ELISA 抗体对
This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
* This package insert must be read in its entirety before using this product.
Human Complement Factor D Sandwich Immunoassay
| Recommended Concentration | Sample | |
|---|---|---|
| ELISA Capture | 0.5-2 μg/mL | Rabbit anti-Human Complement Factor D mAb (Cat. No. RMK0176) |
| ELISA Detection | 0.033-0.133 μg/mL | Rabbit anti-Human Complement Factor D mAb (Cat. No. RMK0177) |
| Standard | 7.81-500 pg/mL | Recombinant Human Complement Factor D Protein (Cat. No. RP01367) |
This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease.
