产品和服务 / 产品类型 / ELISA试剂盒 / ELISA 抗体对
* This package insert must be read in its entirety before using this product.
Human TRAIL R3/ TNFRSF10C Sandwich Immunoassay
| Recommended Concentration | Sample | |
|---|---|---|
| ELISA Capture | 1-4 μg/mL | Rabbit anti-Human TRAIL R3/ TNFRSF10C mAb (Cat. No. RMK0174) |
| ELISA Detection | 0.05-0.2 μg/mL | Rabbit anti-Human TRAIL R3/ TNFRSF10C mAb (Cat. No. RMK0175) |
| Standard | 62.5-4000 pg/mL | Recombinant Human TRAIL R3/ TNFRSF10C Protein |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.
