产品中心 / 产品类型 / ELISA试剂盒 / ELISA 抗体对
This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
* This package insert must be read in its entirety before using this product.
Human p-Tau181 CLIA assay
| Recommended Concentration | Sample | |
|---|---|---|
| CLIA Capture | 1-4ug/mL | Rabbit anti-Human Tau mAb(Cat. No.RMK0025) |
| CLIA Detection | 0.5-2ug/mL | Rabbit anti-Human p-Tau181 mAb(Cat. No.RMK0110) |
| Standard | 0.05-5ng/mL | Recombinant Human p-Tau181 Protein |
Tau is a microtubule-associated protein expressed primarily in neurons. Carboxy-terminal domains of Tau associate with and stabilize microtubule structure, while other domains bind to the plasma membrane. Abnormal Tau phosphorylation may result in the self-assembly of tangles of paired helical and/or straight filaments, which are involved in the pathogenesis of Alzheimer's disease and other neurodegenerative diseases. Properly folded Tau is highly soluble, but when the protein becomes misfolded it forms insoluble aggregates that can damage cytoplasmic functions, interfere with axonal transport and ultimately lead to cell death.
