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* This package insert must be read in its entirety before using this product.
Human VCAM-1 Sandwich Immunoassay
| Recommended Concentration | Sample | ||
|---|---|---|---|
| ELISA | Capture | 1-4 μg/mL | Rabbit anti-Human VCAM-1 mAb (Cat. No. RMK0013) |
| Detection | 0.125-0.5 μg/mL | Rabbit anti-Human VCAM-1 mAb (Cat. No. RMK0014) | |
| Standard | 15.63-1000 pg/mL | Recombinant Human VCAM-1/CD106 Protein (Cat. No. RP00972) |
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.