Flow cytometry analysis of 293T cells with overexpressed mouse FOXP3 using PE Rabbit anti-Mouse FOXP3 mAb (A26227) at 1:20 dilution. clearly classified positive and negative cells.
The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene result in the scurfy phenotype (sf). Alternative splicing results in multiple transcript variants.