Flow cytometry analysis of mouse bone marrow using PE Rabbit anti-Mouse CD162/PSGL-1 mAb (A25949) at 1:200 dilution. clearly classified positive and negative cells.
Involved in leukocyte adhesive activation. Acts upstream of or within leukocyte tethering or rolling. Predicted to be located in plasma membrane raft and uropod. Predicted to be active in plasma membrane. Is expressed in brain and thymus primordium. Human ortholog(s) of this gene implicated in carotid artery disease. Orthologous to human SELPLG (selectin P ligand).
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