Recombinant protein (or fragment).This information is considered to be commercially sensitive.
克隆号
ARC64069
产品形式
Liquid
偶联物
PE. Ex:565nm. Em:574nm.
克隆号
ARC64069
产品形式
Liquid
偶联物
PE. Ex:565nm. Em:574nm.
细胞定位
Cell membrane.
存储缓冲液
Store at 2-8℃. Avoid freeze. Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Flow Cytometry analysis of mouse spleen single-cell suspensions, using PE Rabbit anti-Mouse CD4 mAb (A25933) and PE/Cyanine7 Rabbit anti-Mouse CD8a mAb (A26742). The staining clearly distinguished between positive and negative cell populations.
Flow Cytometry analysis of MC38 tumor microenvironment, using ABflo® 647 Rabbit anti-Mouse CD8a mAb (A23904), PE Rabbit anti-Mouse CD4 mAb (A25933), ABflo® 450 Rabbit anti-Mouse CD45 mAb (A27197) and ABflo® 488 Rabbit anti-Mouse CD11b mAb (A24094), clearly classified positive and negative cells.
Publishing research using A25933? Please let us know so that we can cite the reference in this datasheet.
背景信息
Predicted to enable several functions, including interleukin-16 binding activity; interleukin-16 receptor activity; and protein homodimerization activity. Involved in helper T cell enhancement of adaptive immune response. Acts upstream of or within several processes, including defense response to Gram-negative bacterium; positive regulation of calcium-mediated signaling; and positive regulation of peptidyl-tyrosine phosphorylation. Located in endoplasmic reticulum; external side of plasma membrane; and membrane raft. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and liver and biliary system. Used to study type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in immunodeficiency 79. Orthologous to human CD4 (CD4 molecule).