Flow Cytometry analysis of human umbilical cord hematopoietic stem cells, using ABflo 647 Rabbit anti-Human CD34 mAb(A25894) at 1:100 dilution. The staining clearly distinguished between positive and negative cell populations.
The protein encoded by this gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene.