Flow cytometry analysis of human PBMC using ABflo® 594 Rabbit anti-Human IFN-gamma mAb (A25559) at 1:20 dilution. clearly classified positive and negative cells.
Flow cytometry analysis of human PBMCs using IFN-gamma Rabbit mAb (ARC67550) clearly classified positive and negative cells. The effects of ABclonal and vendor B are similar.
This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases.