Recombinant protein (or fragment).This information is considered to be commercially sensitive.
克隆号
ARC64735
产品形式
Liquid
偶联物
ABflo® 647. Ex:648nm. Em:664nm.
克隆号
ARC64735
产品形式
Liquid
偶联物
ABflo® 647. Ex:648nm. Em:664nm.
细胞定位
Cell membrane, Cell projection, Cell surface, Cytoplasm, Membrane, Secreted, Single-pass type II membrane protein, Single-pass type II membrane protein, invadopodium membrane, lamellipodium membrane, ruffle membrane.
存储缓冲液
Store at 2-8℃. Avoid freeze. Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Flow Cytometry analysis of WI38 cells , using ABflo® 647 Rabbit anti-Human FAP monoclonal Antibody (A24966) at a dilution of 1:50. Compared with the antibody results of Vendor R, the effect is better.
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
