Recombinant protein (or fragment).This information is considered to be commercially sensitive.
克隆号
ARC61149
产品形式
Liquid
偶联物
ABflo® 488. Ex:491nm. Em:516nm.
克隆号
ARC61149
产品形式
Liquid
偶联物
ABflo® 488. Ex:491nm. Em:516nm.
细胞定位
Membrane, Single-pass type I membrane protein.
存储缓冲液
Store at 2-8℃. Avoid freeze. Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
