Flow cytometry analysis of mouse spleen using ABflo® 647 Rabbit anti-Mouse CD25 mAb (A23808) clearly classified positive and negative cells. The effects of ABclonal and vendor B are similar.
Flow cytometry analysis of mouse spleen using ABflo® 647 Rabbit anti-Mouse CD25 monoclonal antibody, the positive and negative cells are clearly classified.
Enables interleukin-2 binding activity and interleukin-2 receptor activity. Acts upstream of or within several processes, including Notch signaling pathway; activation-induced cell death of T cells; and regulation of T cell proliferation. Located in external side of plasma membrane. Is expressed in bone marrow. Used to study Sjogren's syndrome and inflammatory bowel disease. Human ortholog(s) of this gene implicated in immunodeficiency 41; lymphopenia; multiple sclerosis; type 1 diabetes mellitus; and type 1 diabetes mellitus 10. Orthologous to human IL2RA (interleukin 2 receptor subunit alpha).