Recombinant protein (or fragment).This information is considered to be commercially sensitive.
克隆号
AMC0542
产品形式
Liquid
偶联物
PE. Ex:565nm. Em:574nm.
克隆号
AMC0542
产品形式
Liquid
偶联物
PE. Ex:565nm. Em:574nm.
细胞定位
Membrane, Single-pass type I membrane protein.
存储缓冲液
Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.2.
This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia.