SARS-CoV-2 N protein enhances the anti-apoptotic activity of MCL-1 to promote viral replication - PMC
Journal
Signal transduction and targeted therapy
Pancreatic acinar cells-derived sphingosine-1-phosphate contributes to fibrosis of chronic pancreatitis via inducing autophagy and activation of pancreatic stellate
Cell membrane-camouflaged bufalin targets NOD2 and overcomes multidrug resistance in pancreatic cancer
Journal
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy
A novel sprayable thermosensitive hydrogel coupled with zinc modified metformin promotes the healing of skin wound - PMC
Journal
Bioactive materials
Cholesterol-associated lysosomal disorder triggers cell death of hematological malignancy: Dynamic analysis on cytotoxic effects of LW-218
Calcium Supplementation Attenuates Fluoride-Induced Bone Injury Via Pink/Parkin-Mediated Mitophagy and Mitochondrial Apoptosis in Mice
Journal
Journal of hazardous materials
Genome-Scale CRISPR Screen Identifies LAPTM5 driving lenvatinib resistance in hepatocellular carcinoma
SPATA33 is an autophagy mediator for cargo selectivity in germline mitophagy
BPA and low-Se exacerbate apoptosis and autophagy in the chicken bursa of Fabricius by regulating the ROS/AKT/FOXO1 pathway
Journal
The Science of the total environment
New insights into brain injury in chickens induced by bisphenol A and selenium deficiencyMitochondrial reactive oxygen species and mitophagy-apoptosis crosstalk
Journal
The Science of the total environment
Purinergic receptor P2Y12 boosts autoimmune hepatitis through hexokinase 2-dependent glycolysis in T cells - PMC
Journal
International journal of biological sciences
Modulation of miR-29 influences myocardial compliance likely through coordinated regulation of calcium handling and extracellular matrix - PMC
Journal
Molecular therapy. Nucleic acids
CircRNA-IGLL1/miR-15a/RNF43 axis mediates ammonia-induced autophagy in broilers jejunum via Wnt/-catenin pathway
Repression of the AURKA-CXCL5 axis induces autophagic cell death and promotes radiosensitivity in non-small-cell lung cancer
FV-429 induces autophagy blockage and lysosome-dependent cell death of T-cell malignancies via lysosomal dysregulation
The interaction between STING and NCOA4 exacerbates lethal sepsis by orchestrating ferroptosis and inflammatory responses in macrophages - PMC
Journal
Cell death & disease
Battery wastewater induces nephrotoxicity via disordering the mitochondrial dynamics
Isoform-specific mutation in Dystonin-b gene causes late-onset protein aggregate myopathy and cardiomyopathy - PMC
Bisphenol A induces placental ferroptosis and fetal growth restriction via the YAP/TAZ-ferritinophagy axis
Journal
Free radical biology & medicine
Exosomes derived from schwann cells alleviate mitochondrial dysfunction and necroptosis after spinal cord injury via AMPK signaling pathway-mediated mitophagy
Journal
Free radical biology & medicine
Maintaining the Mitochondrial Quality Control System Was a Key Event of Tanshinone IIA against Deoxynivalenol-Induced Intestinal Toxicity - PMC
Journal
Antioxidants (Basel, Switzerland)
Alanyl-Glutamine Protects against Lipopolysaccharide-Induced Liver Injury in Mice via Alleviating Oxidative Stress, Inhibiting Inflammation, and Regulating Autophagy
Journal
Antioxidants (Basel, Switzerland)
SQSTM1/p62 Knockout by Using the CRISPR/Cas9 System Inhibits Migration and Invasion of Hepatocellular Carcinoma - PMC
BECLIN-1-Mediated Autophagy Suppresses Silica Nanoparticle-Induced Testicular Toxicity via the Inhibition of Caspase 8-Mediated Cell Apoptosis in Leydig Cells - PMC
Oroxylin A activates ferritinophagy to induce hepatic stellate cell senescence against hepatic fibrosis by regulating cGAS-STING pathway
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Hexavalent chromium triggers hepatocytes premature senescence via the GATA4/NF-B signaling pathway mediated by the DNA damage response
Journal
Ecotoxicology and environmental safety
Species
Homo sapiens, Mus musculus
Hexavalent chromium inhibits the formation of neutrophil extracellular traps and promotes the apoptosis of neutrophils via AMPK signaling pathway
Journal
Ecotoxicology and environmental safety
FNDC5 inhibits autophagy of bone marrow mesenchymal stem cells and promotes their survival after transplantation by downregulating Sp1 - PMC
Journal
Cell death discovery
FK866 attenuates sepsis-induced acute lung injury through c-jun-N-terminal kinase (JNK)-dependent autophagy
nNovel insights into antidepressant mechanism of Kai Xin San formula: inhibiting NLRP3 inflammasome activation by promoting autophagy
Sophflarine A, a novel matrine-derived alkaloid from Sophora flavescens with therapeutic potential for non-small cell lung cancer through ROS-mediated pyroptosis …
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
Autophagy flux inhibition mediated by lysosomal dysfunction participates in the cadmium exposure-induced cardiotoxicity in swine
Journal
BioFactors (Oxford, England)
High PPT1 expression predicts poor clinical outcome and PPT1 inhibitor DC661 enhances sorafenib sensitivity in hepatocellular carcinoma
Journal
Cancer cell international
Species
Homo sapiens, Mus musculus
Downregulation of miR-29c promotes muscle wasting by modulating the activity of leukemia inhibitory factor in lung cancer cachexia
Modification of lysine deacetylation regulates curcumol-induced necroptosis through autophagy in hepatic stellate cells
Journal
Phytotherapy research : PTR
Calcium/calmodulin dependent protein kinase IV in trophoblast cells under insulin resistance: functional and metabolomic analyses - PMC
Journal
Molecular medicine (Cambridge, Mass.)
Long Non-Coding LEF1-AS1 Sponge miR-5100 Regulates Apoptosis and Autophagy in Gastric Cancer Cells via the miR-5100/DEK/AMPK-mTOR Axis
Journal
International journal of molecular sciences
Activation of Autophagy by Low-Dose Silica Nanoparticles Enhances Testosterone Secretion in Leydig Cells
Journal
International journal of molecular sciences
Silica Nanoparticles Promote Apoptosis in Ovarian Granulosa Cells via Autophagy Dysfunction - PMC
Journal
International journal of molecular sciences
Species
Homo sapiens, Mus musculus
Defective Mitochondrial Dynamics and Protein Degradation Pathways Underlie Cadmium-Induced Neurotoxicity and Cell Death in Huntingtons Disease Striatal Cells - PMC
Journal
International journal of molecular sciences
Mallotucin D, a Clerodane Diterpenoid from Croton crassifolius, Suppresses HepG2 Cell Growth via Inducing Autophagic Cell Death and Pyroptosis - PMC
Journal
International journal of molecular sciences
Bilobalide Exerts Anti-Inflammatory Effects on Chondrocytes Through the AMPK/SIRT1/mTOR Pathway to Attenuate ACLT-Induced Post-Traumatic Osteoarthritis in Rats
Journal
Frontiers in pharmacology
Olmesartan alleviates SARS-CoV-2 envelope protein induced renal fibrosis by regulating HMGB1 release and autophagic degradation of TGF-β1 - PMC
Journal
Frontiers in pharmacology
Species
Homo sapiens,Mus musculus
Electroacupuncture ameliorates AOM/DSS-induced mice colorectal cancer by inhibiting inflammation and promoting autophagy via the SIRT1/miR-215/Atg14 axis - PMC
Species
Mus musculus;Homo sapiens
Hepatotoxicity of the Pesticide Avermectin Exposure to Freshwater-Farmed Carp: Evidence from In Vivo and In Vitro Research
Journal
Journal of agricultural and food chemistry
Folic Acid Protects against Ethanol-Induced Hepatic Mitophagy Imbalance by ROS Scavenging and Attenuating the Elevated Hcy Levels
Journal
Journal of agricultural and food chemistry
Glycyrrhizic acid improves tacrolimusinduced renal injury by regulating autophagy
Journal
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Species
Homo sapiens, Mus musculus
Mitophagy induced by UMI-77 preserves mitochondrial fitness in renal tubular epithelial cells and alleviates renal fibrosis
Journal
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
RRM2 Mediates the Anti-Tumor Effect of the Natural Product Pectolinarigenin on Glioblastoma Through Promoting CDK1 Protein Degradation by Increasing Autophagic Flux
Journal
Frontiers in oncology
Monotropein induces autophagy through activation of the NRF2/PINK axis, thereby alleviating sepsis-induced colonic injury
Journal
International immunopharmacology
A Self-Assembly ICG Nanoparticle Potentiating Targeted Photothermal and Photodynamic Therapy in NSCLC
Journal
ACS biomaterials science & engineering
Dihydroartemisinin inhibits the activation and proliferation of hepatic stellate cells by regulating miR-29b-3p - PMC
Journal
International journal of molecular medicine
Aquaporin 5 maintains lens transparency by regulating the lysosomal pathway using circRNA
Journal
Journal of cellular and molecular medicine
Anthocyanin Oligomers Induce Apoptosis and Autophagy by Inhibiting the mTOR Signaling Pathway in Human Breast Cancer Cells - PMC
Journal
Pharmaceuticals (Basel, Switzerland)
Bletilla striata polysaccharide attenuated the progression of pulmonary fibrosis by inhibiting TGF-1/Smad signaling pathway
Journal
Journal of ethnopharmacology
Huang-Lian-Jie-Du decoction drug-containing serum inhibits IL-1 secretion from D-glucose and PA induced BV2 cells via autophagy/NLRP3 signaling
Journal
Journal of ethnopharmacology
Orphan nuclear receptor NUR77 relieves insulin resistance in HTR-8/SVneo trophoblast cells through activation of autophagy and insulin signaling
Journal
Journal of physiology and biochemistry
Loss of ACTL7A causes small head sperm by defective acrosome-acroplaxome-manchette complex - PMC
Journal
Reproductive biology and endocrinology : RB&E
Nacetylneuraminic acid modulates SQSTM1/p62 sialyationmediated ubiquitination degradation contributing to vascular endothelium dysfunction in experimental
Nucleotide-binding oligomerization domain protein 1 enhances oxygen-glucose deprivation and reperfusion injury in cortical neurons via activation of endoplasmic reticulum stress-mediated autophagy
Clostridium butyricum Alleviates Gut Microbiota Alteration–Induced Bone Loss after Bariatric Surgery by Promoting Bone Autophagy
Journal
The Journal of pharmacology and experimental therapeutics
High Uric Acid Promotes Atherosclerotic Plaque Instability by Apoptosis Targeted Autophagy
Journal
Journal of atherosclerosis and thrombosis
Creatine ameliorates high-fat diet-induced obesity by regulation of lipolysis and lipophagy in brown adipose tissue and liver
Rapamycin extenuates experimental colitis by modulating the gut microbiota
Journal
Journal of gastroenterology and hepatology
Polyphyllin I induces apoptosis and autophagy in temozolomide-resistant glioma via modulation of NRF2 and MAPK-signaling activation
Journal
Biotechnology & genetic engineering reviews
Pralatrexate mediates effective killing of gemcitabine-resistant pancreatic cancer: role of mTOR/4E-BP1 signal pathway - PMC
Cr (VI)-induced overactive mitophagy contributes to mitochondrial loss and cytotoxicity in L02 hepatocytes
Journal
The Biochemical journal
Platonin Protects Against Cerebral Ischemia/Reperfusion Injury in Rats by Inhibiting NLRP3 Inflammasomes via BNIP3/LC3 Signaling Mediated Autophagy
Osthole protects H9c2 cardiomyocytes against trastuzumab-induced damage by enhancing autophagy through the p38MAPK/mTOR signaling pathway
Journal
Toxicology in vitro : an international journal published in association with BIBRA
MicroRNA?16?5p/BIMP1/NF?κB axis regulates autophagy to exert a tumor?suppressive effect on bladder cancer
TRIM21 undergoes phase separation dependent CC domain to regulate autophagy
Journal
Biochemical and biophysical research communications
Vitamin D alleviates hypoxia/reoxygenation-induced injury of human trophoblast HTR-8 cells by activating autophagy
Nicotinic Acid Riboside Regulates Nrf-2/P62-Related Oxidative Stress and Autophagy to Attenuate Doxorubicin-Induced Cardiomyocyte Injury
Journal
BioMed research international
UHMK1 promotes lung adenocarcinoma oncogenesis by regulating the PI3K/AKT/mTOR signaling pathway
Autophagy inhibition mediated by trillin promotes apoptosis in hepatocellular carcinoma cells via activation of mTOR/STAT3 signaling
Journal
Naunyn-Schmiedeberg's archives of pharmacology
Effects of RFRP-3 on an ovariectomized estrogen-primed rat model and HEC-1A human endometrial carcinoma cells - PMC
Journal
Experimental and therapeutic medicine
Isoschaftoside Reverses Nonalcoholic Fatty Liver Disease via Activating Autophagy In Vivo and In Vitro - PMC
Journal
Evidence-based complementary and alternative medicine : eCAM
Ginsenoside Rg3 protects heart against isoproterenol-induced myocardial infarction by activating AMPK mediated autophagy.
Journal
Cardiovascular Diagnosis and Therapy
Nobiletin Alleviated EpithelialMesenchymal Transition of Hepatocytes in Liver Fibrosis Based on AutophagyHippo/YAP Pathway
Journal
Molecular nutrition & food research
A Golgi-resident GPR108 cooperates with E3 ubiquitin ligase Smurf1 to suppress antiviral innate immunity
The Hyperproliferation Mechanism of Cholesteatoma Based on Proteomics: SNCA Promotes Autophagy-Mediated Cell Proliferation through the PI3K/AKT
Journal
Molecular & cellular proteomics : MCP