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Rabbit anti human IgG(LS mutation) specific monoclonal antibody (Clone 6B4) (YR0514)

验证详情
  • Validated
  • Not Recommended
  • Not Tested
  • 验证数据展示
  • 对比数据展示
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货号: YR0514
价 格:  17700.00
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基础信息

Molecular Weight
150kDa
Endotoxin
<1EU/mg (<0.001EU/μg)Determined by LAL gel clotting assay
Sterility
0.2 μm filtration
Aggregation
<5% Determined by SECP
Purity
>95% Determined by SDS-PAGE

产品信息

Production
Purified from cell culture supernatant in an animal-free facility
Purification
Protein A/G
Storage
Store at 2-8℃

背景信息

Related studies have shown that M428L/N434S (LS) mutations in the Fc region of IgG antibodies can prolong the half-life of therapeutic antibodies, optimize the pharmacokinetic characteristics, and reduce the frequency of administration. We developed Rabbit Anti-human IgG-FC (LS mutation) Specific Monoclonal Antibody that effectively captures and stably binds to IgG Fc segment LS mutants. The LS mutant for therapeutic IgG has important application value in pharmacodynamic/pharmacokinetic studies and detection technology.

免疫原信息

Clone
6B4
Isotype
Rabbit IgG
RecommendedIsotype Control(s)
Recommended Dilution Buffer