Human FGFR2 alpha (IIIb) on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
The purity of Human FGFR2 alpha (IIIb) is greater than 95% as determined by SEC-HPLC.
Immobilized Human FGFR2 alpha IIIb, hFc tag at 0.5μg/ml (100μl/Well). Dose response curve for Biotinylated Anti-FGFR2 Ab., hFc Tag with the EC50 of 10.0ng/ml determined by ELISA.
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGF R1 and 2 results in receptors containing all three Ig domains, referred to as the alpha? isoform, or only IgII and IgIII, referred to as the beta? isoform.
