产品和服务 / 产品类型 / ELISA试剂盒 / ELISA 抗体对
This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
No significant cross-reactivity or interference was observed.
Placed at 37°C for 7 days, the stability of the standard curve all conform to CV <10%.
* This package insert must be read in its entirety before using this product.
Human IL-18 Sandwich Immunoassay
| Recommended Concentration | Sample | ||
|---|---|---|---|
| ELISA | Capture | 1-4 μg/mL | Rabbit anti-Human IL-18 mAb (Cat. No. RMK0590) |
| Detection | 0.0125-0.05 μg/mL | Rabbit anti-Human IL-18 mAb (Cat. No. RMK0591) | |
| Standard | 23.44-500 pg/mL | Recombinant Human IL-18 Protein (Cat. No. RP00006) |
The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
