产品和服务 / 产品类型 / ELISA试剂盒 / ELISA 抗体对
This standard curve is only for demonstration purposes. A standard curve should be generated for eachassay.
* This package insert must be read in its entirety before using this product.
Sheep TNF-alpha Sandwich mmunoassay
| Recommended Concentration | Sample | |
|---|---|---|
| ELISA Capture | 1-4 μg/mL | Rabbit anti-Sheep TNF-alpha mAb (Cat. No. RM18031) |
| ELISA Detection | 0.02-0.08 μg/mL | Rabbit anti-Sheep TNF-alpha mAb (Cat. No. RM18032) |
| Standard | 15.63-1000 pg/mL | Recombinant Sheep TNF-alpha Protein |
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity).Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance (By similarity).Plays a role in angiogenesis by inducing VEGF production synergistically with IL1B and IL6 (By similarity).The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
