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Human CRP Sanwich ELISA Immunoassay
| Recommended Concentration | Sample | |
|---|---|---|
| ELISA Capture | 1-4ug/mL | Rabbit anti-Human CRP (CAP)(Cat. No.RM17827) |
| ELISA Detection | 0.029-0.1ug/mL | Rabbit anti-Human CRP (DET)(Cat. No.RM17828) |
| Standard | 0.16-10ng/mL | Recombinant Human CRP Protein |
C-Reactive Protein (CRP), also known as Pentraxin 1, is a non-glycosylated protein in the Pentraxin family that also includes Pentraxin 2/SAP and Pentraxin 3/TSG-14. CRP functions as a sensor and activator of the innate immune response. In humans, it is a major acute-phase protein; its circulating concentration is dramatically elevated at the onset of inflammation. In mice, however, serum CRP levels increase only slightly during inflammation, and the analogous acute phase role is filled by Pentraxin 2. CRP assembles non-covalently into a 110-120 kDa cyclical pentamer. Mature human CRP shares 71% and 64% amino acid (aa) sequence identity with mouse and rat CRP, respectively.
