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Human Galectin 1/LGALS1 Sanwich ELISA Immunoassay
Recommended Concentration | Sample | |
---|---|---|
ELISA Capture | 0.25-1ug/mL | Rabbit anti-Human Galectin 1/LGALS1 (CAP)(Cat. No.RM17806) |
ELISA Detection | 0.0625-0.25ug/mL | Rabbit anti-Human Galectin 1/LGALS1 (DET)(Cat. No.RM17807) |
Standard | 0.78-50ng/mL | Recombinant Human Galectin 1/LGALS1 Protein |
Galectin 1 (Gal-1) is a 14 KDa β-galactose-binding mammalian lectin that is associated with many signaling pathways, immune responses associated with cancer progression, and immune disorders. Inhibition of human Gal-1 is considered as one of the potential approaches to treat cancer because it plays an important role in tumor progression and metastasis by regulating various biological functions, namely apoptosis, angiogenesis, migration, and cellular immune escape.Gal-1 is considered as a biomarker for diagnosis, prognosis, and therapeutic status.Overexpression of Gal-1 has been demonstrated in the progression of many types of cancer, such as osteosarcoma, breast, lung, prostate, melanoma, etc. Gal-1 greatly accelerates the binding kinetics of HIV-1 to susceptible cells, leading to faster viral entry and more robust viral replication through specific binding to CD4 cells. Therefore, Gal-1 is considered a promising molecular target for the development of new cancer and HIV therapeutics.Translated with www.DeepL.com/Translator (free version)