
产品和服务 / 产品类型 / ELISA试剂盒 / ELISA 抗体对
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Mouse IL-6 Sandwich Immunoassay
| Recommended Concentration | Sample | ||
|---|---|---|---|
| ELISA | Capture | 0.5-2 μg/mL | Rabbit anti-Mouse IL-6 mAb (Cat. No. RM17709) |
| Detection | 0.0125-0.05 μg/mL | Rabbit anti-Mouse IL-6 mAb (Cat. No. RM17710) | |
| Standard | 7.81-500 pg/mL | Recombinant Mouse IL-6 Protein (Cat. No.RP01321) | |
| Multiplex | Capture | 3-20 μg/mL | Rabbit anti-Mouse IL-6 mAb (Cat. No. RM17709) |
| Detection | 0.017-2 μg/mL | Rabbit anti-Mouse IL-6 mAb (Cat. No. RM17968) | |
| Standard | 6.86-5000 pg/ml | Recombinant Mouse IL-6 Protein (Cat. No. RP01321) |
Publishing research using RM17709? Please let us know so that we can cite the reference in this datasheet.
Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation leads to the regulation of the immune response, acute-phase reactions and hematopoiesis. The interaction with membrane-bound IL6R and IL6ST stimulates "classic signaling", the restricted expression of the IL6R limits classic IL6 signaling to only a few tissues such as the liver and some cells of the immune system. Whereas the binding of IL6 and soluble IL6R to IL6ST stimulates "trans-signaling". Alternatively, "cluster signaling" occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.