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Rabbit anti-Mouse IL-6 mAb(CAP) (RM17709)

This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

Placed at 37°C for 3 days, the stability of the standard curve all conform to CV <10%.

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货号: RM17709
价 格:   ¥2100
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详细信息

产品名称
Rabbit anti-Mouse IL-6 mAb(CAP)
货号
RM17709
免疫原
Recombinant mouse IL-6 Protein
纯化方式
Affinity purification
同种型
Rabbit IgG
内毒素水平
/
存储溶液
Supplied as a 0.2 μm filtered solution in PBS with 0.05% Proclin 300, pH 7.4.
CrossReactivity
No cross-reactivity in immunoassay with recombinant
Human IL-6, Mouse IL-11
存储条件
Store at -20℃. Avoid repeated freeze-thaw cycles.

* This package insert must be read in its entirety before using this product.

应用

Mouse IL-6 Sandwich Immunoassay

  Recommended
Concentration
Sample
ELISACapture0.5-2 μg/mLRabbit anti-Mouse IL-6 mAb (Cat. No. RM17709)
Detection0.0125-0.05 μg/mLRabbit anti-Mouse IL-6 mAb (Cat. No. RM17710)
Standard7.81-500 pg/mLRecombinant Mouse IL-6 Protein (Cat. No.RP01321)
MultiplexCapture3-20 μg/mLRabbit anti-Mouse IL-6 mAb (Cat. No. RM17709)
Detection0.017-2 μg/mLRabbit anti-Mouse IL-6 mAb (Cat. No. RM17968)
Standard6.86-5000 pg/mlRecombinant Mouse IL-6 Protein (Cat. No. RP01321)

Publishing research using RM17709? Please let us know so that we can cite the reference in this datasheet.

背景信息

Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation leads to the regulation of the immune response, acute-phase reactions and hematopoiesis. The interaction with membrane-bound IL6R and IL6ST stimulates "classic signaling", the restricted expression of the IL6R limits classic IL6 signaling to only a few tissues such as the liver and some cells of the immune system. Whereas the binding of IL6 and soluble IL6R to IL6ST stimulates "trans-signaling". Alternatively, "cluster signaling" occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.

基因ID
Swiss Prot
别名
CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2; IL6