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Biotinylated Human IL-2 Monoclonal Antibody, Rabbit MAb(DET) (RM17591)

From the comparison of the standard curve, it is found that ABclonal has high sensitivity.

This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

No significant cross-reactivity or interference was observed.

Placed at 37°C for 3 days, the stability of the standard curve all conform to CV <10%.

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货号: RM17591
价 格:  29525.00
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详细信息

RM17591
Biotinylated Human IL-2 Monoclonal Antibody, Rabbit MAb(DET)
样本类型
Supplied as a 0.2μm filtered solution in PBS with 0.05% Proclin300, PH 7.4.
反应时间
Human
检测范围
Recombinant Human IL2 Protein
Ala21-Thr153
Accession #P60568
组分
Secreted.
储存条件
Store at -20℃
安全说明
No cross-reactivity in ELISA with recombinant
rmIL-2,rrIL-2,rhIL-2R,rhIL-1a,rhIL-1b,rhIL-2Ra,rhIL-4,rhIL-7,rhIL-9,rhIL-15
For research purposes only. Not for therapeutic or diagnostic purposes in humans or animals.

* This package insert must be read in its entirety before using this product.

背景信息

This gene is a member of the interleukin 2 (IL2) cytokine subfamily which includes IL4, IL7, IL9, IL15, IL21, erythropoietin, and thrombopoietin. The protein encoded by this gene is a secreted cytokine produced by activated CD4+ and CD8+ T lymphocytes, that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2R) is a heterotrimeric protein complex whose gamma chain is also shared by IL4 and IL7. The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.