Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy
Application
Lipid peroxidation and antioxidant determination
URI alleviates tyrosine kinase inhibitors-induced ferroptosis by reprogramming lipid metabolism in p53 wild-type liver cancers - PMC
Journal
Nature communications
Application
Lipid peroxidation assay
Inhibition of CARM1-Mediated Methylation of ACSL4 Promotes Ferroptosis in Colorectal Cancer - PMC
Journal
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Application
Measurement of ROS and Lipid ROS Levels
A NIRII Photoactivatable "ROS Bomb" with HighDensity Cu2OSupported MoS2 Nanoflowers for Anticancer Therapy
Journal
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Engineering dual catalytic nanomedicine for autophagy-augmented and ferroptosis-involved cancer nanotherapy
Application
Confocal fluorescence images of LLC cells
YTHDC1 as a tumor progression suppressor through modulating FSP1-dependent ferroptosis suppression in lung cancer
Journal
Cell death and differentiation
SNORD88C guided 2′-O-methylation of 28S rRNA regulates SCD1 translation to inhibit autophagy and promote growth and metastasis in non-small cell lung cancer
Journal
Cell death and differentiation
Application
lipid peroxidation assay
Neuronal STAT3/HIF-1α/PTRF axis-mediated bioenergetic disturbance exacerbates cerebral ischemia-reperfusion injury via PLA2G4A
Application
Lipid peroxidation and antioxidant assays
EP1 activation inhibits doxorubicin-cardiomyocyte ferroptosis via Nrf2 - PMC
Application
C11-BODIPY assay
Species
Homo sapiens,Rattus norvegicus
Cancer-associated fibroblasts impair the cytotoxic function of NK cells in gastric cancer by inducing ferroptosis via iron regulation - PMC
Application
reactive oxygen species (ROS) assays
Butyrate reverses ferroptosis resistance in colorectal cancer by inducing c-Fos-dependent xCT suppression - PMC
Application
C11-BODIPY assay
Semaphorin 5A suppresses ferroptosis through activation of PI3K-AKT-mTOR signaling in rheumatoid arthritis - PMC
Journal
Cell death & disease
Application
fluorescent probe
Genome-wide CRISPR screening reveals ADCK3 as a key regulator in sensitizing endometrial carcinoma cells to MPA therapy
Journal
British journal of cancer
Targeting NRF2 uncovered an intrinsic susceptibility of acute myeloid leukemia cells to ferroptosis - PMC
Journal
Experimental hematology & oncology
Efficacy of a novel glioma therapy based on ferroptosis induced by layered double hydroxide loaded with simvastatin
Journal
Environmental research
Old targets, new strategy: Apigenin-7-O-β-d-(-6″-p-coumaroyl)-glucopyranoside prevents endothelial ferroptosis and alleviates intestinal ischemia-reperfusion injury through HO-1 and MAO-B inhibition
Journal
Free radical biology & medicine
Exogenous melatonin ameliorates steroid-induced osteonecrosis of the femoral head by modulating ferroptosis through GDF15-mediated signaling - PMC
Journal
Stem cell research & therapy
Discovery of Novel Potent Covalent Glutathione Peroxidase 4 Inhibitors as Highly Selective Ferroptosis Inducers for the Treatment of Triple-Negative Breast Cancer
Journal
Journal of medicinal chemistry
Application
Lipid peroxidation determination
Identification of Lipocalin 2 as a Ferroptosis-Related Key Gene Associated with Hypoxic-Ischemic Brain Damage via STAT3/NF-κB Signaling Pathway - PMC
Journal
Antioxidants (Basel, Switzerland)
Application
Lipid Peroxidation
Ferroptosis-Related Gene GCLC Is a Novel Prognostic Molecular and Correlates with Immune Infiltrates in Lung Adenocarcinoma - PMC
Application
Lipid Peroxidation
Identification of Lipocalin 2 as a Potential Ferroptosis-related Gene in Ulcerative Colitis
Journal
Inflammatory bowel diseases
Application
Lipid Peroxidation Assay
Inhibition of NRF2 enhances the acute myeloid leukemia cell death induced by venetoclax via the ferroptosis pathway - PMC
Journal
Cell death discovery
Application
Biochemical detection
ACSF2-mediated ferroptosis is involved in ulcerative colitis
Application
Bodipy C11 assay
Astaxanthin attenuates ferroptosis via Keap1-Nrf2/HO-1 signaling pathways in LPS-induced acute lung injury
Application
Lipid peroxidation assay
High Level of Uric Acid Promotes Atherosclerosis by Targeting NRF2-Mediated Autophagy Dysfunction and Ferroptosis
Journal
Oxidative medicine and cellular longevity
Application
Lipid ROS Assay
KCNA1 promotes the growth and invasion of glioblastoma cells through ferroptosis inhibition via upregulating SLC7A11 - PMC
Journal
Cancer cell international
Radiosensitizing effects of pyrogallol-loaded mesoporous or-ganosilica nanoparticles on gastric cancer by amplified ferroptosis - PMC
Journal
Frontiers in bioengineering and biotechnology
Application
Detection of lipid peroxidation
Activation of p62-NRF2 Axis Protects against Doxorubicin-Induced Ferroptosis in Cardiomyocytes: A Novel Role and Molecular Mechanism of Resveratrol
Journal
The American journal of Chinese medicine
Application
Lipid Reactive Oxygen Species (ROS) Assay
Glycyrrhizin arginine salt protects against cisplation-induced acute liver injury by repressing BECN1-mediated ferroptosis - PMC
Journal
Frontiers in pharmacology
Application
Lipid ROS assay
Dapagliflozin alleviates myocardial ischemia/reperfusion injury by reducing ferroptosis via MAPK signaling inhibition - PMC
Journal
Frontiers in pharmacology
GSK-J4, a Specific Histone Lysine Demethylase 6A Inhibitor, Ameliorates Lipotoxicity to Cardiomyocytes via Preserving H3K27 Methylation and Reducing Ferroptosis - PMC
Journal
Frontiers in cardiovascular medicine
Species
Homo sapiens, Mus musculus
OIT3 serves as a novel biomarker of hepatocellular carcinoma by mediating ferroptosis via regulating the arachidonic acid metabolism - PMC
Journal
Frontiers in oncology
Application
Lipid ROS measurement
Liproxstatin-1 alleviates LPS/IL-13-induced bronchial epithelial cell injury and neutrophilic asthma in mice by inhibiting ferroptosis
Journal
International immunopharmacology
Application
Lipid ROS assay
CircRNA-ST6GALNAC6 increases the sensitivity of bladder cancer cells to erastin-induced ferroptosis by regulating the HSPB1/P38 axis
Journal
Laboratory investigation; a journal of technical methods and pathology
Fisetin suppresses ferroptosis through Nrf2 and attenuates intervertebral disc degeneration in rats
Journal
European journal of pharmacology
Modified Shoutai Pill inhibited ferroptosis to alleviate recurrent pregnancy loss
Journal
Journal of ethnopharmacology
Application
lipid ROS detection
Butyrate enhances erastin-induced ferroptosis of osteosarcoma cells via regulating ATF3/SLC7A11 pathway
Journal
European journal of pharmacology
Application
Lipid peroxidation measurement
Inhibition of SLC7A11-GPX4 signal pathway is involved in aconitine-induced ferroptosis in vivo and in vitro
Journal
Journal of ethnopharmacology
Application
Lipid peroxidation assay
Dimethyl fumarate protects against hepatic ischemia-reperfusion injury by alleviating ferroptosis via the NRF2/SLC7A11/HO-1 axis
Journal
Cell cycle (Georgetown, Tex.)
Application
Cell metabolism assay
Fluoride resistance capacity in mammalian cells involves global gene expression changes associate with ferroptosis
Journal
Chemico-biological interactions
Identification of ferroptosis-related genes for overall survival prediction in hepatocellular carcinoma - PMC
Journal
Scientific reports
Suppressing Endoplasmic Reticulum Stress Alleviates LPS-Induced Acute Lung Injury via Inhibiting Inflammation and Ferroptosis
Resveratrol protects against deoxynivalenol-induced ferroptosis in HepG2 cells
Shikonin Could Be Used to Treat Tubal Pregnancy via Enhancing Ferroptosis Sensitivity - PMC
Journal
Drug design, development and therapy
Hypoxia promotes the growth and metastasis of ovarian cancer cells by suppressing ferroptosis via upregulating SLC2A12
Journal
Experimental cell research
IFNγ enhances ferroptosis by increasing JAK‑STAT pathway activation to suppress SLCA711 expression in adrenocortical carcinoma
Application
Lipid peroxidation detectio
The PTBP1-NCOA4 axis promotes ferroptosis in liver cancer cells - PMC
Application
fluorescent probe staining
Silencing of METTL3 suppressed ferroptosis of myocardial cells by m6A modification of SLC7A11 in a YTHDF2 manner
Journal
Journal of bioenergetics and biomembranes
Application
Biochemical detection
TRPM7 mediates endoplasmic reticulum stress and ferroptosis in sepsis-induced myocardial injury
Journal
Journal of bioenergetics and biomembranes
Application
Lipid peroxidation
ZNF8-miR-552-5p Axis Modulates ACSL4-Mediated Ferroptosis in Hepatocellular Carcinoma
Journal
DNA and cell biology
Targeting FAM134B-mediated reticulophagy activates sorafenib-induced ferroptosis in hepatocellular carcinoma
Journal
Biochem Biophys Res Commun
Procyanidin alleviates ferroptosis and inflammation of LPS-induced RAW264. 7 cell via the Nrf2/HO-1 pathway
Journal
Naunyn-Schmiedeberg's archives of pharmacology
Application
Lipid peroxidation assay
CircRHOT1 restricts gastric cancer cell ferroptosis by epigenetically regulating GPX4 - PMC
Journal
Journal of gastrointestinal oncology
Erucic acid improves the progress of pregnancy complicated with systemic lupus erythematosus by inhibiting the effector function of CD8+ T cells - PMC
Nodal promotes colorectal cancer survival and metastasis through regulating SCD1-mediated ferroptosis resistance - PMC
Journal
Cell death & disease
UHRF1-mediated ferroptosis promotes pulmonary fibrosis via epigenetic repression of GPX4 and FSP1 genes - PMC
Journal
Cell death & disease