Flow Cytometry analysis of human whole blood, using PE Rabbit anti-Human/Mouse FOXP3 mAb (A27686) and ABflo® 488 Rabbit anti-Human CD4 mAb (A26597). The staining clearly distinguished between positive and negative cell populations.
The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
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