Recombinant protein (or fragment).This information is considered to be commercially sensitive.
克隆号
ARC59957
产品形式
Liquid
偶联物
PE. Ex:565nm. Em:574nm.
克隆号
ARC59957
产品形式
Liquid
偶联物
PE. Ex:565nm. Em:574nm.
细胞定位
Cell membrane, Cytoplasmic vesicle, Lysosome lumen, Single-pass type I membrane protein.
存储缓冲液
Store at 2-8℃. Avoid freeze. Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Publishing research using A24595? Please let us know so that we can cite the reference in this datasheet.
背景信息
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
K1D_FC_01.jpg?t=1779264607)
