Flow Cytometry analysis of human kidney cancer tissue, using ABflo®647 Rabbit anti-Human EGFR monoclonal antibody at a dilution of 1:100, the positive signal transition is obvious.
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
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