Flow Cytometry analysis of human lymphocyte, using ABflo® 488 Rabbit anti-Human VCAM-1/CD106 monoclonal antibody , the positive signal transition is obvious.
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.
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