Artificial Macrophage with Hierarchical Nanostructure for Biomimetic Reconstruction of Antitumor Immunity - PMC
Journal
Nano-micro letters
Pathogenesis-adaptive polydopamine nanosystem for sequential therapy of ischemic stroke - PMC
Journal
Nature communications
The protective effects of benzaldehyde combined with albendazole against brain injury induced by Angiostrongylus cantonensis infection in mice.
Journal
International journal of antimicrobial agents
Astaxanthine attenuates cisplatin ototoxicity in vitro and protects against cisplatin-induced hearing loss in vivo
Journal
Acta pharmaceutica Sinica. B
Inhibition of PRKAA/AMPK (Ser485/491) phosphorylation by crizotinib induces cardiotoxicity via perturbing autophagosome-lysosome fusion
Downregulation of apoptotic repressor AVEN exacerbates cardiac injury after myocardial infarction
Journal
Proceedings of the National Academy of Sciences of the United States of America
Species
Homo sapiensMus musculus
Platelet Membrane‐fused Circulating Extracellular Vesicles Protect the Heart from Ischemia/reperfusion Injury
Journal
Advanced healthcare materials
Ignored role of polyphenol in boosting reactive oxygen species generation for polyphenol/chemodynamic combination therapy - PMC
Journal
Materials today. Bio
The therapeutic effect of Tanshinone IIA in mouse astrocytes after treatment with Angiostrongylus cantonensis fifth-stage larval excretory-secretory products
Journal
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
U (Vi) Exposure Induces Apoptosis and Pyroptosis in Raw264. 7 Cells
H1N1 Influenza Virus-Infected Nasal Mucosal Epithelial Progenitor Cells Promote Dendritic Cell Recruitment and Maturation
Journal
Frontiers in immunology
Biological testing of chitosan-collagen-based porous scaffolds loaded with PLGA/Triamcinolone microspheres for ameliorating endoscopic dissection-related stenosis in oesophagus
N-Acetyl-l-cysteine restores reproductive defects caused by Ggt1 deletion in mice
Characterization of a polysaccharide from Sanghuangporus vaninii and its antitumor regulation via activation of the p53 signaling pathway in breast cancer MCF-7 …
Journal
Int J Biol Macromol
Species
Sanghuangporus vaninii
Luteolin Alleviates AflatoxinB 1-Induced Apoptosis and Oxidative Stress in the Liver of Mice through Activation of Nrf2 Signaling Pathway
Journal
Antioxidants (Basel)
Biochanin A Ameliorates Nephropathy in High-Fat Diet/Streptozotocin-Induced Diabetic Rats: Effects on NF-kB/NLRP3 Axis, Pyroptosis, and Fibrosis - PMC
Journal
Antioxidants (Basel, Switzerland)
miR-135a Suppresses Granulosa Cell Growth by Targeting Tgfbr1 and Ccnd2 during Folliculogenesis in Mice
LTB4R Promotes the Occurrence and Progression of Clear Cell Renal Cell Carcinoma (ccRCC) by Regulating the AKT/mTOR Signaling Pathway - PMC
Palmatine ameliorates high fat diet induced impaired glucose tolerance
Innate sensing of picornavirus infection involves cGAS-STING-mediated antiviral responses triggered by mitochondrial DNA release
Bisdemethoxycurcumin alleviates vandetanib-induced cutaneous toxicity in vivo and in vitro through autophagy activation
Journal
Biomed Pharmacother
Angelica sinensis polysaccharides ameliorated 5-Fluorouracil-induced damage of early B cell progenitors by alleviating oxidative stress of IL-7 producing
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Hydroxytyrosol Ameliorates Intervertebral Disc Degeneration and Neuropathic Pain by Reducing Oxidative Stress and Inflammation - PMC
Journal
Oxidative medicine and cellular longevity
Lactational exposure to Deoxynivalenol causes mammary gland injury via inducing inflammatory response and impairing blood-milk barrier integrity in mice
Journal
Ecotoxicology and environmental safety
Hexavalent chromium inhibits the formation of neutrophil extracellular traps and promotes the apoptosis of neutrophils via AMPK signaling pathway
Journal
Ecotoxicology and environmental safety
Cepharanthine, a regulator of keap1-Nrf2, inhibits gastric cancer growth through oxidative stress and energy metabolism pathway - PMC
Journal
Cell death discovery
Copper Induces Cognitive Impairment in Mice via Modulation of Cuproptosis and CREB Signaling - PMC
Sophflarine A, a novel matrine-derived alkaloid from Sophora flavescens with therapeutic potential for non-small cell lung cancer through ROS-mediated pyroptosis …
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
Pinocembrin alleviates pyroptosis and apoptosis through ROS elimination in random skin flaps via activation of SIRT3
Journal
Phytotherapy research : PTR
Shikonin Attenuates Cochlear Spiral Ganglion Neuron Degeneration by Activating Nrf2-ARE Signaling Pathway
Journal
Frontiers in molecular neuroscience
Metabolomics and Transcriptomics Analyses of Curcumin Alleviation of Ochratoxin A-Induced Hepatotoxicity - PMC
Journal
International journal of molecular sciences
Mallotucin D, a Clerodane Diterpenoid from Croton crassifolius, Suppresses HepG2 Cell Growth via Inducing Autophagic Cell Death and Pyroptosis - PMC
Journal
International journal of molecular sciences
Xanthones from Gentianella acuta (Michx.) Hulten Ameliorate Colorectal Carcinoma via the PI3K/Akt/mTOR Signaling Pathway - PMC
Journal
International journal of molecular sciences
Changes in the Expression and Functional Activities of C-X-C Motif Chemokine Ligand 13 (CXCL13) in Hyperplastic Prostate - PMC
Journal
International journal of molecular sciences
Species
Homo sapiens,Rattus norvegicus
Crizotinib induces pulmonary toxicity by blocking autophagy flux in alveolar epithelial cells
Journal
Biochemical pharmacology
Galectin-7 promotes cisplatin efficacy by facilitating apoptosis and G3BP1 degradation in cervical cancer
Journal
Biochemical pharmacology
Panax notoginseng saponin R1 attenuates allergic rhinitis through AMPK/Drp1 mediated mitochondrial fission
Journal
Biochemical pharmacology
Curdione Relieved Isoproterenol-Induced Myocardial Damage through Inhibiting Oxidative Stress and Apoptosis
Journal
The American journal of Chinese medicine
Melatonin induces cell cycle arrest and suppresses tumor invasion in urinary bladder urothelial carcinoma - PMC
Hsp22 pretreatment protects against LPS-induced hippocampal injury by alleviating neuroinflammation and apoptosis by regulating the NLRP3/Caspase1/IL-1β signaling pathway in mice - PMC
miR-153-3p Targets βII Spectrin to Regulate Formaldehyde-Induced Cardiomyocyte Apoptosis
Journal
Frontiers in cardiovascular medicine
KLK4 promotes proliferation, migration, invasion, and pro-angiogenesis of endometrial stromal cells via regulation of regulation of BDNF production in endometriosis
Journal
The American journal of pathology
Searching for novel MDM2/MDMX dual inhibitors through a drug repurposing approach
Journal
Journal of enzyme inhibition and medicinal chemistry
Myricetin Suppresses Ovarian Cancer In Vitro by Activating the p38/Sapla Signaling Pathway and Suppressing Intracellular Oxidative Stress
Journal
Frontiers in oncology
Carnosic Acid Suppresses the Development of Oral Squamous Cell Carcinoma via Mitochondrial-Mediated Apoptosis
6-Gingerol protects against cerebral ischemia/reperfusion injury by inhibiting NLRP3 inflammasome and apoptosis via TRPV1/FAF1 complex dissociation-mediated autophagy
Journal
Int Immunopharmacol
Procyanidin B2 ameliorates the progression of osteoarthritis: An in vitro and in vivo study
Journal
International immunopharmacology
Caffeic acid modulates activation of neutrophils and attenuates sepsis-induced organ injury by inhibiting 5-LOX/LTB4 pathway
Journal
International immunopharmacology
Effects of prenatal acetaminophen exposure at different stages, doses and courses on articular cartilage of offspring mice
Journal
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
4-Hydroxyderricin Promotes Apoptosis and Cell Cycle Arrest through Regulating PI3K/AKT/mTOR Pathway in Hepatocellular Cells
The Protective Effect and Mechanism of a Phytochemical Extract from the Wild Vegetable Shutou (Crateva unilocularis Buch.) against Acetaminophen-Induced Liver Injury in Mice - PMC
Journal
Foods (Basel, Switzerland)
Exploring the Underlying Mechanism of Ren-Shen-Bai-Du Powder for Treating Inflammatory Bowel Disease Based on Network Pharmacology and Molecular Docking - PMC
Journal
Pharmaceuticals (Basel, Switzerland)
Scutellarin attenuates oxidative stress and neuroinflammation in cerebral ischemia/reperfusion injury through PI3K/Akt-mediated Nrf2 signaling pathways
Journal
European journal of pharmacology
The apoptotic effects of soybean agglutinin were induced through three different signal pathways by down-regulating cytoskeleton proteins in IPEC-J2 cells - PMC
Journal
Scientific reports
In Vitro Anticancer Activity of Methanolic Extract of Justicia adhatoda Leaves with Special Emphasis on Human Breast Cancer Cell Line - PMC
Journal
Molecules (Basel, Switzerland)
Glucogallin Attenuates RAW 264.7 Cells from Arsenic Trioxide Induced Toxicity via the NF-κB/NLRP3 Pathway - PMC
Journal
Molecules (Basel, Switzerland)
DHCR7 promotes tumorigenesis via activating PI3K/AKT/mTOR signalling pathway in bladder cancer
Journal
Cellular Signalling
RIOK2 Inhibitor NSC139021 Exerts Anti-Tumor Effects on Glioblastoma via Inducing Skp2-Mediated Cell Cycle Arrest and Apoptosis
miR-140-3p inhibits colorectal cancer progression and its liver metastasis by targeting BCL9 and BCL2
Chlorpyrifos-mediated mitochondrial calcium overload induces EPC cell apoptosis via ROS/AMPK/ULK1
Journal
Fish & shellfish immunology
Maternal exposure to PM2. 5 decreases ovarian reserve in neonatal offspring mice through activating PI3K/AKT/FoxO3a pathway and ROS-dependent NF-κB pathway
Dimethoxytolyl propylresorcinol induces apoptosis and mitophagy in human leukemia cells through the PI3K/AKT pathway - PMC
Species
Dianella ensifolia,Homo sapiens
ZNRF2 as an oncogene is transcriptionally regulated by CREB1 in breast cancer models
Glucose fluctuation accelerates cardiac injury of diabetic mice via sodium-dependent glucose cotransporter 1 (SGLT1)
Journal
Arch Biochem Biophys
Curcumin attenuates diphenyl phosphateinduced apoptosis in GC2spd (ts) cells through activated autophagy via the Nrf2/P53 pathway
Journal
Environmental toxicology
Athelia rolfsii Exopolysaccharide Protection Against Kidney Injury in Lead-Exposed Mice via Nrf2 Signaling Pathway
Journal
Biological trace element research
Methyl-CpG-binding domain 3 (Mbd3) is an important regulator for apoptosis in mouse embryonic stem cells
Knockdown of SGLT1 prevents the apoptosis of cardiomyocytes induced by glucose fluctuation via relieving oxidative stress and mitochondrial dysfunction
Journal
Biochemistry and cell biology = Biochimie et biologie cellulaire
Inhibition of miR-423-5p exerts neuroprotective effects in an experimental rat model of cerebral ischemia/reperfusion injury
Ginsenoside Rb2 alleviates myocardial ischemia/reperfusion injury in rats through SIRT1 activation
Melatonin protects cochlear hair cells from nicotine‐induced injury through inhibiting apoptosis, inflammation, oxidative stress and endoplasmic reticulum stress
Journal
Basic & clinical pharmacology & toxicology
Role of Ero1 in cognitive impairment induced by chronic hypoxia
MiR-20a-5p overexpression prevented diabetic cardiomyopathy via inhibition of cardiomyocyte apoptosis, hypertrophy, fibrosis and JNK/NF-B signalling pathway
Journal
Journal of biochemistry
Knockdown of Mmu-circ-0001380 Attenuates Myocardial Ischemia/Reperfusion Injury via Modulating miR-106b-5p/Phlpp2 Axis
Journal
Journal of cardiovascular translational research
Allicin ameliorates sepsis-induced acute kidney injury through Nrf2/HO-1 signaling pathway
Journal
Journal of natural medicines
ZnSO4 Protects against premature ovarian failure through PI3K/AKT/GSK3β signaling pathway
Inhibition of LAMP3 mediates the protective effect of vitamin D against hypoxia/reoxygenation in trophoblast cells - PMC
Journal
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
Pathological Changes and Expression of JAK-STAT Signaling Pathway Hallmark Proteins in Rat Retinas at Different Time Points After Retinal Ischemia Reperfusion Injury
Journal
Pathology oncology research : POR
Network pharmacology and experimental validation to study the potential mechanism of Tongguanteng injection in regulating apoptosis in osteosarcoma - PMC
Journal
BMC complementary medicine and therapies
Protective effects of miR?155?5p silencing on IFN?γ?induced apoptosis and inflammation in salivary gland epithelial cells
Tanshinone I alleviates steroid-induced osteonecrosis of femoral heads and promotes angiogenesis: in vivo and in vitro studies - PMC
Journal
Journal of orthopaedic surgery and research
Species
Rattus norvegicus, Homo sapiens
Renal Protective Mechanisms of Shenyuan Particle in Db/Db Mice: A Study Based on Network Pharmacology - PMC
Journal
Evidence-based complementary and alternative medicine : eCAM
Asperuloside Promotes Apoptosis of Cervical Cancer Cells through Endoplasmic Reticulum Stress-Mitochondrial Pathway
Journal
Chinese journal of integrative medicine
ATF3 regulates oxidative stress and extracellular matrix degradation via p38/Nrf2 signaling pathway in pelvic organ prolapse
Bone marrow mesenchymal stem cell derived exosomal miR-455-5p protects against spinal cord ischemia reperfusion injury
SMYD1 alleviates septic myocardial injury by inhibiting endoplasmic reticulum stress
Journal
Bioscience, biotechnology, and biochemistry
NeiyiKangfu tablets control the progression of endometriosis through inhibiting RAF/MEK/ERK signal pathway by targeting RKIP
Journal
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
miR-100-5p is upregulated in multiple myeloma and involves in the pathogenesis of multiple myeloma through targeting MTMR3
Journal
Hematology (Amsterdam, Netherlands)
Engeletin ameliorates sevoflurane‐induced cognitive impairment by activating PPAR‐gamma in neonatal mice
Journal
Neuropathology : official journal of the Japanese Society of Neuropathology
Knockdown of HDAC9 attenuates sepsis-induced myocardial injury and inflammatory response
Journal
Experimental animals
Acetylation stabilizes the signaling protein WISP2 by preventing its degradation to suppress the progression of acute myeloid leukemia
Journal
The Journal of biological chemistry