Cell membrane-camouflaged bufalin targets NOD2 and overcomes multidrug resistance in pancreatic cancer
Journal
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy
Bioengineered Bacteriophage-Like Nanoparticles as RNAi Therapeutics to Enhance Radiotherapy against Glioblastomas
Bioengineered Bacteriophage-Like Nanoparticles as RNAi Therapeutics to Enhance Radiotherapy against Glioblastomas
Enzyme-like biomimetic oral-agent enabling modulating gut microbiota and restoring redox homeostasis to treat inflammatory bowel disease - PMC
Journal
Bioactive materials
An injectable and adaptable hydrogen sulfide delivery system for modulating neuroregenerative microenvironment - PMC
Ozone Exposure Affects Corneal Epithelial Fate by Promoting mtDNA Leakage and cGAS/STING Activation
Journal
Journal of hazardous materials
Genipin-activating PPAR impedes CCR2-mediated macrophage infiltration into postoperative liver to suppress recurrence of hepatocellular carcinoma - PMC
Journal
International journal of biological sciences
Genipin-activating PPAR impedes CCR2-mediated macrophage infiltration into postoperative liver to suppress recurrence of hepatocellular carcinoma - PMC
Journal
International journal of biological sciences
SLC7A2 deficiency promotes hepatocellular carcinoma progression by enhancing recruitment of myeloid-derived suppressors cells
Species
Homo sapiens, Mus musculus
AMPK-autophagy-mediated inhibition of microRNA-30a-5p alleviates morphine tolerance via SOCS3-dependent neuroinflammation suppression
Journal
Journal of neuroinflammation
Amelioration of Lupus Serum-Induced Skin Inflammation in CD64-Deficient Mice
Journal
Frontiers in immunology
The regulatory effect of NF-B signaling pathway on biomineralization and shell regeneration in pearl oyster, Pinctada fucata
Journal
International journal of biological macromolecules
Semaphorin 7A interacts with nuclear factor NF-kappa-B p105 via integrin β1 and mediates inflammation - PMC
Journal
Cell communication and signaling : CCS
Trichodermin inhibits the growth of oral cancer through apoptosis-induced mitochondrial dysfunction and HDAC-2-mediated signaling
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Aldehyde Dehydrogenase 2 Protects the Kidney from Ischemia-Reperfusion Injury by Suppressing the IκBα/NF-κB/IL-17C Pathway - PMC
Journal
Oxidative medicine and cellular longevity
Inhibition of Brd4 alleviates osteoarthritis pain via suppression of neuroinflammation and activation of Nrf2mediated antioxidant signaling
Journal
British Journal of Pharmacology
STING/NF-κB/IL-6-Mediated Inflammation in Microglia Contributes to Spared Nerve Injury (SNI)-Induced Pain Initiation
Journal
J Neuroimmune Pharmacol
Tanshinone IIA protects intestinal epithelial cells from deoxynivalenol-induced pyroptosis
Journal
Ecotoxicology and environmental safety
Heparanase induces necroptosis of microvascular endothelial cells to promote the metastasis of hepatocellular carcinoma
Agmatine-mediated inhibition of NMDA receptor expression and amelioration of dyskinesia via activation of Nrf2 and suppression of HMGB1/RAGE/TLR4/MYD88/NF …
Inhibition of SGLT1 protects against glycemic variability-induced cardiac damage and pyroptosis of cardiomyocytes in diabetic mice
PIGU promotes hepatocellular carcinoma progression through activating NF-κB pathway and increasing immune escape
Protective Effect of Rhus chinensis Mill. Fruits on 3,5-Diethoxycarbonyl-1,4-Dihydrocollidine-Induced Cholestasis in Mice via Ameliorating Oxidative Stress and Inflammation - PMC
HOXA1 participates in VSMC-to-macrophage-like cell transformation via regulation of NF-κB p65 and KLF4: a potential mechanism of atherosclerosis pathogenesis - PMC
Journal
Molecular medicine (Cambridge, Mass.)
Confusoside, a dihydrochalcone glucoside, prevents acetaminophen-induced liver injury by modulating the Keap1-Nrf2/Nf-κB/Caspase signaling pathway
Lycopene Ameliorates Atrazine-Induced Pyroptosis in Spleen via Suppressing the Ox-mtDNA/Nlrp3 Inflammasome Pathway
Aloe-Emodin Ameliorates Cecal Ligation and Puncture-Induced Sepsis
Journal
International journal of molecular sciences
Application
ELISA, WB, IHC
Methotrexate-Induced Alteration of Renal Aquaporins 1 and 2, Oxidative Stress and Tubular Apoptosis Can Be Attenuated by Omega-3 Fatty Acids Supplementation - PMC
Journal
International journal of molecular sciences
The Extracts of Dendrobium Alleviate Dry Eye Disease in Rat Model by Regulating Aquaporin Expression and MAPKs/NF-κB Signalling - PMC
Journal
International journal of molecular sciences
The novel TAK1 inhibitor handelin inhibits NF-κB and AP-1 activity to alleviate elastase-induced emphysema in mice
Transcriptome Analysis of the Inhibitory Effect of Sennoside A on the Metastasis of Hepatocellular Carcinoma Cells
Calf Thymus Polypeptide Restrains the Growth of Colorectal Tumor via Regulating the Intestinal Microbiota-Mediated Immune Function - PMC
Journal
Frontiers in pharmacology
Melatonin induces cell cycle arrest and suppresses tumor invasion in urinary bladder urothelial carcinoma - PMC
TNFR2 promotes pancreatic cancer proliferation, migration, and invasion via the NF-B signaling pathway - PMC
Rosmarinic Acid Inhibits Platelet Aggregation and Neointimal Hyperplasia In Vivo and Vascular Smooth Muscle Cell Dedifferentiation, Proliferation, and Migration In
Journal
Journal of agricultural and food chemistry
Puerarin improves diabetic wound healing via regulation of macrophage M2 polarization phenotype - PMC
Isobavachalcone's Alleviation of Pyroptosis Contributes to Enhanced Apoptosis in Glioblastoma: Possible Involvement of NLRP3
Journal
Molecular neurobiology
The Protective Effects of Ginseng Polysaccharides and Their Effective Subfraction against Dextran Sodium Sulfate-Induced Colitis
Journal
Foods (Basel, Switzerland)
Silencing LncRNA SNHG16 suppresses the diabetic inflammatory response by targeting the miR-212-3p/NF-B signaling pathway - PMC
Journal
Diabetology & metabolic syndrome
Mechanisms of resveratrol against diabetic wound by network pharmacology and experimental validation - PMC
Journal
Annals of medicine
BAY61?3606 attenuates neuroinflammation and neurofunctional damage by inhibiting microglial Mincle/Syk signaling response after traumatic brain injury
ATL I, Acts as a SIRT6 Activator to Alleviate Hepatic Steatosis in Mice via Suppression of NLRP3 Inflammasome Formation - PMC
Journal
Pharmaceuticals (Basel, Switzerland)
Activation of SIRT-1 Pathway by Nanoceria Sheds Light on Its Ameliorative Effect on Doxorubicin-Induced Cognitive Impairment (Chemobrain): Restraining Its Neuroinflammation, Synaptic Dysplasticity and Apoptosis - PMC
Journal
Pharmaceuticals (Basel, Switzerland)
Mechanistic Insights on the In Vitro Antibacterial Activity and In Vivo Hepatoprotective Effects of Salvinia auriculata Aubl against Methotrexate-Induced Liver Injury
Journal
Pharmaceuticals (Basel, Switzerland)
'Pterocephalodes hookeri-Onosma hookeri'decoction protects against LPS-induced pulmonary inflammation via inhibiting TLR4/NF-B signaling pathway
Journal
Journal of ethnopharmacology
Analysis of pharmacodynamic components, targets and synergistic action mechanism of Fuyuan Shenghua granule for the treatment of medical-induced incomplete
Journal
Journal of ethnopharmacology
Kuijie decoction ameliorates ulcerative colitis by affecting intestinal barrier functions, gut microbiota, metabolic pathways and Treg/Th17 balance in mice
Journal
Journal of ethnopharmacology
Potential Anti-Gout Properties of Wuwei Shexiang Pills Based on Network Pharmacology and Pharmacological Verification
Journal
Journal of ethnopharmacology
Efficacy of curculigoside in protecting against ischemic brain injury through regulation of oxidative stress and NF-κB and PI3K/Akt expression
Journal
Journal of ethnopharmacology
Prebiotics modulate the microbiotagutbrain axis and ameliorate cognitive impairment in APP/PS1 mice
Journal
European journal of nutrition
LncRNA H19 Mitigates Oxidized Low-Density Lipoprotein Induced Pyroptosis via Caspase-1 in Raw 264.7 Cells
Qing-Luo-Yin Alleviated Experimental Arthritis in Rats by Disrupting Immune Feedback Between Inflammatory T Cells and Monocytes: Key Evidences from Its Effects on Immune Cell Phenotypes
Journal
Journal of inflammation research
Inhibition of miRNA-1-Mediated Inflammation and Autophagy by Astragaloside IV Improves Lipopolysaccharide-Induced Cardiac Dysfunction in Rats
Journal
Journal of inflammation research
PK2/PKRs pathway is involved in the protective effect of artemisinin against trimethyltin chloride-induced hippocampal injury
Alpha-Chymotrypsin Protects Against Acute Lung, Kidney, and Liver Injuries and Increases Survival in CLP-Induced Sepsis in Rats Through Inhibition of TLR4/NF-κB Pathway - PMC
Journal
Drug design, development and therapy
Downregulation of HHLA2 inhibits ovarian cancer progression via the NF-B signaling pathway and suppresses the expression of CA9
Journal
Cellular immunology
Smad7 alleviates glomerular mesangial cell proliferation via the ROS-NF-B pathway
Journal
Experimental cell research
Quercetin and Vitamin C Mitigate Cobalt Chloride-Induced Hypertension through Reduction in Oxidative Stress and Nuclear Factor Kappa Beta (NF-Kb) Expression in Experimental Rat Model
Journal
Biological trace element research
Intermittent high glucose induces pyroptosis of rat H9C2 cardiomyocytes via sodium-glucose cotransporter 1
Emodin suppresses oxaliplatininduced neuropathic pain by inhibiting COX2/NFB mediated spinal inflammation
Journal
Journal of biochemical and molecular toxicology
Design of novel balanced COX inhibitors based on natural antiinflammatory ascidian metabolites and celecoxib
Suppression of neuronal apoptosis and glial activation with modulation of Nrf2/HO-1 and NF-kB signaling by curcumin in streptozotocin-induced diabetic spinal cord central neuropathy - PMC
Journal
Frontiers in neuroanatomy
Synthesis of nature product kinsenoside analogues with anti-inflammatory activity
Journal
Bioorganic & medicinal chemistry
MicroRNA?16?5p/BIMP1/NF?κB axis regulates autophagy to exert a tumor?suppressive effect on bladder cancer
Electroacupuncture Alleviates Neuroinflammation by Inhibiting the HMGB1 Signaling Pathway in Rats with Sepsis-Associated Encephalopathy - PMC
Toxoplasma gondii rhoptry protein (TgROP18) enhances the expression of pro-inflammatory factor in LPS/IFN--induced murine BV2 microglia cells via NF-B signal
Preventive effect of dioscin against monosodium urate-mediated gouty arthritis through inhibiting inflammasome NLRP3 and TLR4/NF-κB signaling pathway activation: an in vivo and in vitro study
Electroacupuncture Zusanli (ST36) Relieves Somatic Pain in Colitis Rats by Inhibiting Dorsal Root Ganglion Sympathetic-Sensory Coupling and Neurogenic Inflammation - PMC
SHCBP1 contributes to the proliferation and self-renewal of cervical cancer cells and activation of the NF-κB signaling pathway through EIF5A - PMC
Fluorofenidone Attenuates Renal Interstitial Fibrosis by Enhancing Autophagy and Retaining Mitochondrial Function
Journal
Cell biochemistry and biophysics
The Therapeutic Role of PNU-74654 in Hepatocellular Carcinoma May Involve Suppression of NF-κB Signaling - PMC
Journal
Medicina (Kaunas, Lithuania)
Alleviating effect of lycorine on CFA-induced arthritic pain via inhibition of spinal inflammation and oxidative stress - PMC
Journal
Experimental and therapeutic medicine
TLR4-IN-C34 protects against acute kidney injury via modulating TLR4/MyD88/NF-κb axis, MAPK, and apoptosis - PMC
Journal
Iranian journal of basic medical sciences
FERMT1 knockdown attenuates inflammation induced by intracerebral hemorrhage in rats via NLRP3/NF-B pathway
Journal
Experimental animals
Species
Mus musculus,Rattus norvegicus
BCL11B Upregulates the Expression of RelA in T Cells Stimulated with Staphylococcal Enterotoxin A
Journal
Bulletin of experimental biology and medicine