Neonatal Tissue‐derived Extracellular Vesicle Therapy (NEXT): A Potent Strategy for Precision Regenerative Medicine
Journal
Advanced materials (Deerfield Beach, Fla.)
An Ellagic Acid Coordinated CopperBased Nanoplatform for Efficiently Overcoming Cancer Chemoresistance by Cuproptosis and Synergistic Inhibition of Cancer
Journal
Small (Weinheim an der Bergstrasse, Germany)
A Single-Cell Transcriptomic Atlas of Human Skin Aging
Journal
Developmental Cell
Solid fuel derived PM2. 5 induced oxidative stress and according cytotoxicity in A549 cells: The evidence and potential neutralization by green tea
Journal
Environment international
A Single-Cell Transcriptomic Atlas of Human Skin Aging
Injectable extracellular vesicle-released self-assembling peptide nanofiber hydrogel as an enhanced cell-free therapy for tissue regeneration
Journal
Journal of Controlled Release : Official Journal of the Controlled Release Society
KIF11 promotes cell proliferation via ERBB2/PI3K/AKT signaling pathway in gallbladder cancer.
A self-assembling peptide hydrogel-based drug co-delivery platform to improve tissue repair after ischemia-reperfusion injury
Journal
Acta Biomaterialia
Injectable self-assembling peptide nanofiber hydrogel as a bioactive 3D platform to promote chronic wound tissue regeneration
Choline-induced SLC5A7 impairs colorectal cancer growth by stabilizing p53 protein
Species
Homo sapiens, Mus musculus
Pou3f1 mediates the effect of Nfatc3 on ulcerative colitis-associated colorectal cancer by regulating inflammation - PMC
Journal
Cellular & molecular biology letters
Application
Histological staining
LncRNA NORAD Mediates the Proliferation and Apoptosis of Diffuse Large-B-Cell Lymphoma via Regulation of miR-345-3p/TRAF6 Axis
Journal
Archives of medical research
Dual PI3K/mTOR inhibitor PF-04979064 regulates tumor growth in gastric cancer and enhances drug sensitivity of gastric cancer cells to 5-FU
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
The effects of prenatal azithromycin exposure on offspring ovarian development at different stages, doses, and courses
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Paneth Cells Protect against Acute Pancreatitis via Modulating Gut Microbiota Dysbiosis
Species
Homo sapiens, Mus musculus
Knockdown of HSP110 attenuates hypoxia-induced pulmonary hypertension in mice through suppression of YAP/TAZ-TEAD4 pathway - PMC
Journal
Respiratory research
HNRNPC, a predictor of prognosis and immunotherapy response based on bioinformatics analysis, is related to proliferation and invasion of NSCLC cells - PMC
Journal
Respiratory research
In vitro evaluation of nanoplastics using human lung epithelial cells, microarray analysis and co-culture model
Journal
Ecotoxicol Environ Saf
Circular RNA circRPPH1 promotes breast cancer progression via circRPPH1-miR-512-5p-STAT1 axis
YEATS domain-containing 2 (YEATS2), targeted by microRNA miR-378a-5p, regulates growth and metastasis in head and neck squamous cell carcinoma
Zinc finger protein 521 attenuates osteoarthritis via the histone deacetylases 4 in the nucleus - PMC
Pentadecapeptide BPC 157 efficiently reduces radiation-induced liver injury and lipid accumulation through Kruppel-like factor 4 upregulation both in vivo and in vitro
Anti-inflammatory role and mechanism of microRNA-92b-3p in the progression of hypoxic pulmonary hypertension
Maternal intermittent fasting in mice disrupts the intestinal barrier leading to metabolic disorder in adult offspring - PMC
Journal
Communications biology
miR‐136‐5p/FZD4 axis is critical for Wnt signaling‐mediated myogenesis and skeletal muscle regeneration
Journal
Journal of cellular physiology
A novel role of VEPH1 in regulating AoSMC phenotypic switching
Journal
Journal of cellular physiology
Prognostic signature composed of transcription factors accurately predicts the prognosis of gastric cancer patients
Lactate Induces Aberration in the miR-30a-DBF4 Axis to Promote the Development of Gastric Cancer and Weakens the Sensitivity to 5-Fu
MiRNAs expression profiling of bovine (Bos taurus) testes and effect of bta-mir-146b on proliferation and apoptosis in bovine male germline stem cells
Journal
International journal of molecular sciences
Necroptosis Inhibition by Hydrogen Sulfide Alleviated Hypoxia-Induced Cardiac Fibroblasts Proliferation via Sirtuin 3
PARM1 Drives Smooth Muscle Cell Proliferation in Pulmonary Arterial Hypertension via AKT/FOXO3A Axis - PMC
Journal
International journal of molecular sciences
Species
Mus musculus,Rattus norvegicus
Suppression of Cell Tumorigenicity by Non-neural Pro-differentiation Factors via Inhibition of Neural Property in Tumorigenic Cells
Journal
Front Cell Dev Biol
ANGPTL4 Regulates Psoriasis via Modulating Hyperproliferation and Inflammation of Keratinocytes - PMC
Journal
Frontiers in pharmacology
Species
Homo sapiens, Mus musculus
Fecal microbiota transplantation mitigates vaginal atrophy in ovariectomized mice
lncRNA HCG11 suppresses cell proliferation in hormone receptor-positive breast cancer via SRSF1/β-catenin - PMC
MiR-1254 suppresses HO-1 expression through seed region-dependent silencing and non-seed interaction with TFAP2A transcript to attenuate NSCLC growth.
Tumor-promoting properties of karyopherin β1 in melanoma by stabilizing Ras-GTPase-activating protein SH3 domain-binding protein 1
Journal
Cancer gene therapy
Momordica. charantia -Derived Extracellular Vesicles-Like Nanovesicles Protect Cardiomyocytes Against Radiation Injury via Attenuating DNA Damage and Mitochondria Dysfunction
Journal
Frontiers in cardiovascular medicine
The LPS induced pyroptosis exacerbates BMPR2 signaling deficiency to potentiate SLEPAH
The Influenza Virus H5N1 Infection Can Induce ROS Production for Viral Replication and Host Cell Death in A549 Cells Modulated by Human Cu/Zn Superoxide Dismutase (SOD1) Overexpression
Protective effect and mechanism of nicotinamide adenine dinucleotide against optic neuritis in mice with experimental autoimmune encephalomyelitis
Journal
Int Immunopharmacol
Restoration of miR-328a-5p function curtails hypoxic pulmonary hypertension through a mechanism involving PIN1/GSK3/-catenin axis
Journal
International immunopharmacology
Species
Homo sapiens, Rattus norvegicus
Toxic effect window of ovarian development in female offspring mice induced by prenatal prednisone exposure with different doses and time - PMC
Journal
Journal of ovarian research
Hepatitis B core antigen modulates exosomal miR-135a to target vesicle-associated membrane protein 2 promoting chemoresistance in hepatocellular carcinoma
Journal
World journal of gastroenterology
Nimbolide inhibits tumor growth by restoring hepatic tight junction protein expression and reduced inflammation in an experimental hepatocarcinogenesis
Journal
World J Gastroenterol
Enhanced proliferation and differentiation of HO-1 gene-modified bone marrow-derived mesenchymal stem cells in the acute injured kidney
Journal
international journal of molecular medicine
Calpain-1 mediates vascular remodelling and fibrosis via HIF-1α in hypoxia-induced pulmonary hypertension
Journal
Journal of cellular and molecular medicine
The role of PKN1 in glioma pathogenesis and the antiglioma effect of raloxifene targeting PKN1
Journal
Journal of cellular and molecular medicine
Pretreatment with the active fraction of Rhodiola tangutica (Maxim.) SH Fu rescues hypoxia-induced potassium channel inhibition in rat pulmonary artery smooth muscle cells
BPA induces placental trophoblast proliferation inhibition and fetal growth restriction by inhibiting the expression of SRB1
Journal
Environmental science and pollution research international
Role of Wnt/-catenin signaling pathway in ameloblast differentiation in relevance to dental fluorosis
Journal
Chemico-biological interactions
Effects of miR-101-3p on goat granulosa cells in vitro and ovarian development in vivo via STC1
Journal
J Anim Sci Biotechnol
HTRA3 transcriptionally inhibited by FOXP1 suppresses tumorigenesis of osteosarcoma via the PTEN/PI3K/AKT pathway
Journal
Biochimica et biophysica acta. Molecular cell research
The silencing of NREP aggravates OA cartilage damage through the TGF-1/Smad2/3 pathway in chondrocytes - PMC
Journal
Journal of orthopaedic translation
LncRNA MT1JP plays a protective role in intrahepatic cholangiocarcinoma by regulating miR-18a-5p/FBP1 axis
β-Asarone Exerts Antioxidative Effects on H 2 O 2-Stimulated PC12 Cells by Activating Nrf2/HO-1 Pathway
SPOCK2 and SPRED1 function downstream of EZH2 to impede the malignant progression of lung adenocarcinoma in vitro and in vivo - PMC
Tripartite motif containing 63, regulated by E26 transformation specific variant 4, facilitates the thyroid carcinoma progression and the AKT, p38, and ERK signaling pathways
Journal
Molecular and cellular endocrinology
CLEC12B suppresses lung cancer progression by inducing SHP-1 expression and inactivating the PI3K/AKT signaling pathway
SEZ6L2, regulated by USF1, accelerates the growth and metastasis of breast cancer
Journal
Experimental cell research
Type 2 Diabetic Mellitus Inhibits Skin Renewal through Inhibiting WNT-Dependent Lgr5+ Hair Follicle Stem Cell Activation in C57BL/6 Mice
Journal
Journal of diabetes research
Dietary supplementation of salidroside alleviates liver lipid metabolism disorder and inflammatory response to promote hepatocyte regeneration via PI3K/AKT/Gsk3- pathway - PMC
Involvement of Ataxin-3 (ATXN3) in the malignant progression of pancreatic cancer via deubiquitinating HDAC6
Journal
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
Possible mechanism of CHI3L1 promoting tonsil lymphocytes proliferation in children with obstructive sleep apnea syndrome
Therapeutic effect of low-intensity pulsed ultrasound on temporomandibular joint injury induced by chronic sleep deprivation in rats
Journal
American journal of translational research
An exploration of the effect of Chinese herbal compound on the occurrence and development of large intestine cancer and intestinal flora - PMC
FOXG1 regulates the proliferation and apoptosis of human lung cancer cells - PMC
Cytoprotective effect of chlorogenic acid against hydrogen peroxide-induced oxidative stress in MC3T3-E1 cells through PI3K/Akt-mediated Nrf2/HO-1 signaling pathway.
Jagged 2 inhibition attenuates hypoxia-induced mitochondrial damage and pulmonary hypertension through Sirtuin 1 signaling - PMC
Hepatoprotective effect of crude polysaccharide isolated from Lycium barbarum L. against alcohol-induced oxidative damage involves Nrf2 signaling
Inhibiting effect of microRNA-187-3p on osteogenic differentiation of osteoblast precursor cells by suppressing cannabinoid receptor type 2.
Journal
Differentiation; research in biological diversity
A novel BRDT inhibitor NHWD870 shows potential as a male contraceptive in mice
Journal
Acta biochimica et biophysica Sinica
The Optimal Regimen for the Treatment of Temporomandibular Joint Injury Using Low-Intensity Pulsed Ultrasound in Rats with Chronic Sleep Deprivation.
Journal
BioMed Research International
Quantitative proteomic analysis revealed changes in protein synthesis and mitochondrial functions after acute DNA damage in mouse neural stem cells
Journal
Neuroscience letters
Prognostic impact of the combination of HIF-1 and GLUT1 in patients with oesophageal squamous cell carcinoma - PMC
Propofol suppresses cell proliferation in gastric cancer cells through NRF2‐mediated polyol pathway
Journal
Clinical and experimental pharmacology & physiology
Blockade of ZFX Alleviates Hypoxia-Induced Pulmonary Vascular Remodeling by Regulating the YAP Signaling
Journal
Cardiovascular toxicology
Involvement of calcineurin/NFATc4 pathway in a single-prolonged stress-based rat model of post-traumatic stress disorder.
Journal
Molecular biology reports
ENPP1 deletion causes mouse osteoporosis via the MKK3/p38 MAPK/PCNA signaling pathway - PMC
Journal
Journal of orthopaedic surgery and research
Shen Shuai II Recipe Attenuates Renal Interstitial Fibrosis by Improving Hypoxia via the IL-1β/c-Myc Pathway
Journal
Evid Based Complement Alternat Med
Chrysophanol Regulates Cell Death, Metastasis, and Reactive Oxygen Species Production in Oral Cancer Cell Lines
Journal
Evid Based Complement Alternat Med
Tectoridin ameliorates proliferation and inflammation in TNF-α-induced HFLS-RA cells via suppressing the TLR4/NLRP3/NF-κB signaling pathway
Early growth response 2, a novel target of pelvic organ prolapse, is highly expressed in anterior vaginal wall tissues with pelvic organ prolapse
Journal
Histochemistry and cell biology
GLIS Family Zinc Finger 3 Promotes Triple-Negative Breast Cancer Progression by Inducing Cell Proliferation, Migration and Invasion, and Activating the NF
Journal
Biological & pharmaceutical bulletin
Rab11a promotes the malignant progression of ovarian cancer by inducing autophagy
CircRRAS2 promotes myogenic differentiation of bovine MuSCs and is a novel regulatory molecule of muscle development
Journal
Animal biotechnology
Low dose TGF-β1 can improve vohwinkel syndrome by promoting the proliferation of keratinocytes
Non-alcoholic fatty liver disease promotes breast cancer progression through upregulated hepatic fibroblast growth factor 21 - PMC
Journal
Cell death & disease
OSR1 downregulation indicates an unfavorable prognosis and activates the NF-B pathway in ovarian cancer - PMC
Journal
Discover. Oncology
Hexokinase 2 confers radio-resistance in hepatocellular carcinoma by promoting autophagy-dependent degradation of AIMP2 - PMC
Journal
Cell death & disease
Protective effect of hydroxysafflor yellow A on MSCs against senescence induced by D-galactose
Journal
Chinese herbal medicines
Single-cell transcriptome reveals core cell populations and androgen-RXFP2 axis involved in deer antler full regeneration
Journal
Cell regeneration (London, England)
A Lipidated Peptide with Mitochondrial Membrane Localization in Human A549 Lung Cells: From Enhanced Cell-Penetrating Properties to Biological Activity Mechanism
Journal
ACS applied bio materials