Recombinant Human Bcl-2 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 25 kDa.
Immobilized Human BCL-XL Protein at 2 μg/mL (100 μL/well) can bind BCL2 with a linear range of 3.9-421 ng/mL.
This protein is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma.
