YR36/WKS1-mediated phosphorylation of PsbO, an extrinsic member of photosystem II, inhibits photosynthesis and confers stripe rust resistance in wheat
Cloning of wheat keto-acyl thiolase 2B reveals a role of jasmonic acid in grain weight determination
Cytoplasmic Escape of Mitochondrial DNA Mediated by Mfn2 Downregulation Promotes Microglial Activation via cGasSting Axis in Spinal Cord Injury
Ag/TiO2 nanohybrids induce fibrosis-related epithelial-mesenchymal transition in lung epithelial cells and the influences of silver content and silver particle size
Journal
The Science of the total environment
Longitudinal detection of subcategorized CD44v6+ CTCs and circulating tumor endothelial cells (CTECs) enables novel clinical stratification and improves prognostic
LINC00941 promotes pancreatic cancer malignancy by interacting with ANXA2 and suppressing NEDD4L-mediated degradation of ANXA2 - PMC
Journal
Cell death & disease
Microglia-derived TNF-α contributes to RVLM neuronal mitochondrial dysfunction via blocking the AMPK-Sirt3 pathway in stress-induced hypertension - PMC
Journal
Journal of neuroinflammation
Species
Mus musculus,Rattus norvegicus
Two-dimensional nanovermiculite and polycaprolactone electrospun fibers composite scaffolds promoting diabetic wound healing - PMC
Journal
Journal of nanobiotechnology
MiR-93-5p promotes granulosa cell apoptosis and ferroptosis by the NF-kB signaling pathway in polycystic ovary syndrome - PMC
Journal
Frontiers in immunology
Characterization of myeloperoxidase and its contribution to antimicrobial effect on extracellular traps in flounder (Paralichthys olivaceus) - PMC
Journal
Frontiers in immunology
Ginsenoside Rg5 allosterically interacts with P2RY12 and ameliorates deep venous thrombosis by counteracting neutrophil NETosis and inflammatory response - PMC
Journal
Frontiers in immunology
NSC-derived exosomes enhance therapeutic effects of NSC transplantation on cerebral ischemia in mice - PMC
Histone lysine methyltransferases MpDot1 and MpSet9 are involved in the production of lovastatin and MonAzPs by histone crosstalk modification
Journal
International Journal of Biological Macromolecules
STING promotes ferroptosis through NCOA4-dependent ferritinophagy in acute kidney injury
Journal
Free radical biology & medicine
Dopamine D1 receptor-mediated activation of the ERK signaling pathway is involved in the osteogenic differentiation of bone mesenchymal stem cells
Journal
Stem Cell Research & Therapy
High temperature suppressed SSC self-renewal through S phase cell cycle arrest but not apoptosis.
Journal
Stem cell research & therapy
Xianlinglianxiafang Inhibited the growth and metastasis of triple-negative breast cancer via activating PPAR/AMPK signaling pathway
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Species
Mus musculus, Homo sapiens
Targeting the lncMST-EPRS/HSP90AB1 complex as novel therapeutic strategy for T-2 toxin-induced growth retardation
Journal
Ecotoxicology and environmental safety
Long noncoding RNA CERS6-AS1 modulates glucose metabolism and tumor progression in hepatocellular carcinoma by promoting the MDM2/p53 signaling pathway - PMC
Journal
Cell death discovery
Discovery of novel nitrogenous heterocyclic-containing quinoxaline-1, 4-di-N-oxides as potent activator of autophagy in M. tb-infected macrophages
Journal
European journal of medicinal chemistry
Rhein ameliorates lipopolysaccharide-induced intestinal barrier injury via modulation of Nrf2 and MAPKs.
Ameliorative Effect of Mannuronate Oligosaccharides on Hyperuricemic Mice via Promoting Uric Acid Excretion and Modulating Gut Microbiota - PMC
Astaxanthin Augmented the AntiHepatocellular Carcinoma Efficacy of Sorafenib Through the Inhibition of the JAK2/STAT3 Signaling Pathway and Mitigation of
Journal
Molecular nutrition & food research
Astaxanthin supplementation assists sorafenib in slowing skeletal muscle atrophy in H22 tumsor‐bearing mice via reversing abnormal glucose metabolism
Journal
Molecular nutrition & food research
Endoplasmic Reticulum Stress Mediated NLRP3 Inflammasome Activation and Pyroptosis in THP-1 Macrophages Infected with Bacillus Calmette-Guérin - PMC
Journal
International journal of molecular sciences
Parvalbumin-positive neurons in the medial vestibular nucleus contribute to vestibular compensation through commissural inhibition - PMC
Journal
Frontiers in cellular neuroscience
Linking Phospho-Gonadotropin Regulated Testicular RNA Helicase (GRTH/DDX25) to Histone Ubiquitination and Acetylation Essential for Spermatid Development During Spermiogenesis.
Journal
Frontiers in Cell and Developmental Biology
Identification of an Integrase That Responsible for Precise Integration and Excision of Riemerella anatipestifer Genomic Island.
Journal
Frontiers in Microbiology
Species
Riemerella anatipestifer
Involvement of POMC neurons in LEAP2 regulation of food intake and body weight - PMC
Journal
Frontiers in endocrinology
Salvianolic Acid Ameliorates Pressure Overload-Induced Cardiac Endothelial Dysfunction via Activating HIF1/HSF1/CD31 Pathway
Journal
The American journal of Chinese medicine
Maternal Exposure to Cetylpyridinium Chloride Impairs Oogenesis by Causing Mitochondria Disorder in Neonates
Journal
Environmental toxicology and pharmacology
Design, synthesis, and evaluation of novel benzoylhydrazone derivatives as Nur77 modulators with potent antitumor activity against hepatocellular carcinoma - PMC
Journal
Journal of enzyme inhibition and medicinal chemistry
Chronic stress-induced elevation of melanin-concentrating hormone in the locus coeruleus inhibits norepinephrine production and associated with
Journal
The international journal of neuropsychopharmacology
Gestational dibutyl phthalate exposure impairs primordial folliculogenesis in mice through autophagy activation and NOTCH2 signal interruption
Journal
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Critical role of p21 on olaquindox-induced mitochondrial apoptosis and S-phase arrest involves activation of PI3K/AKT and inhibition of Nrf2/HO-1pathway
Journal
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
CXCL20a, a Teleost-Specific Chemokine That Orchestrates Direct Bactericidal, Chemotactic, and Phagocytosis-Killing–Promoting Functions, Contributes to Clearance of Bacterial Infections
Edaravone dexborneol ameliorates cognitive impairment by regulating the NF-B pathway through AHR and promoting microglial polarization towards the M2
Journal
European journal of pharmacology
Species
Homo sapiens, Mus musculus
Prophylactic effects of sporoderm-removed Ganoderma lucidum spores in a rat model of streptozotocin-induced sporadic Alzheimer's disease
Journal
Journal of ethnopharmacology
Isoflurane Rescue Schizophrenia-Related Deficits through Parvalbumin-Positive Neurons in the Dentate Gyrus - PMC
Blockade of Notch1 Signaling Alleviated Podocyte Injury in Lupus Nephritis Via Inhibition of NLRP3 Inflammasome Activation
DUSP5 (dual-specificity protein phosphatase 5) suppresses BCG-induced autophagy via ERK 1/2 signaling pathway
Species
Mycobacterium tuberculosis
18-Glycyrrhetinic Acid Alleviates P. multocida-Induced Vascular Endothelial Inflammation by PARP1-Mediated NF-B and HMGB1 Signalling Suppression in PIEC Cells - PMC
Journal
Infection and drug resistance
Aerobic glycolysis and tumor progression of hepatocellular carcinoma are mediated by ubiquitin of P53 K48-linked regulated by TRIM37
Journal
Experimental cell research
MALDI-MS-based biomarker analysis of extracellular vesicles from human lung carcinoma cells
MY11 exerts antitumor effects through activation of the NF-κB/PUMA signaling pathway in breast cancer - PMC
Journal
Investigational new drugs
Dimethyl fumarate attenuates pain behaviors in osteoarthritis rats
via induction of Nrf2-mediated mitochondrial biogenesis - PMC
Xiaoliu Pingyi Pecipe Inhibits Lung Pre-Metastatic Niche Formation and Prevents Myeloid-Derived Suppressor Cells Recruitment - PMC
Journal
Integrative cancer therapies
Integrating network pharmacology and experimental validation to explore the mechanisms of luteolin in alleviating fumonisin B1induced intestinal inflammatory injury
Journal
Toxicon : official journal of the International Society on Toxinology
Transcriptome Analysis in High Temperature Inhibiting Spermatogonial Stem Cell Differentiation In Vitro
Journal
Reproductive sciences (Thousand Oaks, Calif.)
The Reduction of Tau Hyperphosphorylation by Cornel Iridoid Glycosides Is Mediated by Their Influence on Calpain Activity
Journal
Evidence-based complementary and alternative medicine : eCAM
G-CSF reduces loss of dopaminergic neurons by inhibiting TNF-α and IL-1β in mouse model of Parkinson's disease
Journal
The International journal of neuroscience
Calcitriol attenuates vascular remodeling in association with alteration of ppET-1/ETBR/eNOS and ETAR expression in acute and chronic phases of kidney ischemia …
Journal
Canadian journal of physiology and pharmacology
Engeletin ameliorates sevoflurane‐induced cognitive impairment by activating PPAR‐gamma in neonatal mice
Journal
Neuropathology : official journal of the Japanese Society of Neuropathology
The spike protein of SARS-CoV-2 induces inflammation and EMT of lung epithelial cells and fibroblasts through the upregulation of GADD45A - PMC
Journal
Open medicine (Warsaw, Poland)
Expression of a Mycoparasite Protease in Plant Petals Suppresses the Petal-Mediated Infection by Necrotrophic Pathogens
Species
Coniothyrium minitans