产品和服务 / 产品类型 / ELISA试剂盒 / ELISA 抗体对

Rabbit anti-Human cTnI mAb (CAP) (RM17653)

This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

All(1)|
货号: RM17653
促销价:   ¥2100
抗体定制服务咨询 |
商城订购

详细信息

产品名称
Rabbit anti-Human cTnI mAb (CAP)
货号
RM17653
免疫原
Nature Human cTnI Protein
纯化方式
Affinity purification
同种型
Rabbit IgG
存储溶液
Supplied as a 0.2um filtered solution in PBS with 0.1%Braveds MB-1,PH 7.4.
CrossReactivity
No cross-reactivity in multiplex assay with analogues.
存储条件
Store at -20℃. Avoid freeze / thaw cycles. Preservative:0.05%ProClin 300.Avoid repeated freeze-thaw cycles.

* This package insert must be read in its entirety before using this product.

应用

Human cTnI multiplex assay

 Recommended
Concentration
Sample
Capture6ug/106Rabbit anti-Human cTnI mAb (CAP)(Cat. No. RM17653)
Detection0.25-1ug/mlRabbit anti-Human cTnI mAb (DET)(Cat. No. RM17654)
Standard5.5-4000pg/mLNature Human cTnI Protein

背景信息

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). Troponin I is useful in making a diagnosis of heart failure, and of ischemic heart disease. An elevated level of troponin is also now used as indicator of acute myocardial injury in patients hospitalized with moderate/severe Coronavirus Disease 2019 (COVID-19). Such elevation has also been associated with higher risk of mortality in cardiovascular disease patients hospitalized due to COVID-19.

>