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Rabbit anti-Human IL-10 mAb (RM17644)

This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

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货号: RM17644
促销价:   ¥2100
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详细信息

产品名称
Rabbit anti-Human IL-10 mAb
货号
RM17644
免疫原
Recombinant Human IL-10 Protein
Ser19-Asn178
Accession #P22301
纯化方式
Affinity purification
同种型
Rabbit IgG
存储溶液
Supplied as a 0.2μm filtered solution in PBS with 0.05% Proclin300, PH 7.4.
CrossReactivity
No cross-reactivity in multiplex assay with recombinant
rIL-10,,mIL-10
存储条件
Store at -20℃.Avoid repeated freeze-thaw cycles.

* This package insert must be read in its entirety before using this product.

应用

Human IL-10 ELISA, Multiplex

  Recommended
Concentration
Sample
ELISACapture1-4ug/mLRabbit anti-Human IL-10 mAb (Cat. No.RM17644)
Detection0.25-1ug/mLRabbit anti-Human IL-10 mAb(Cat. No.RM17638)
Standard3.9-250pg/mLRecombinant Human IL-10 Protein (Cat. No.RP00093)
MultiplexCapture10ug/106Rabbit anti-Human IL-10 mAb (Cat. No. RM17643)
Detection0.5-2ug/mLRabbit anti-Human IL-10 mAb (Cat. No. RM17644)
Standard1.4-1000pg/mLRecombinant Human IL-10 Protein

背景信息

The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.

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