产品和服务 / 产品类型 / ELISA试剂盒 / ELISA 抗体对
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Human AMH/MIS Sandwich Immunoassay
Recommended Concentration | Sample | |
---|---|---|
ELISA Capture | 1-4ug/mL | Rabbit anti-Human AMH/MIS mAb(CAP)(Cat. No. RM17623) |
ELISA Detection | 0.1-0.4ug/mL | Human AMH/MIS Monoclonal Antibody, Rabbit MAb(DET)(Cat. No. RM17624) |
Standard | 78-5000pg/mL | Recombinant Human AMH Protein with His tag(Cat. No. RM00045) |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome.