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Rabbit anti-Human AMH/MIS mAb(CAP) (RM17623)

This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

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货号: RM17623
促销价:   ¥2100
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详细信息

产品名称
Rabbit anti-Human AMH/MIS mAb(CAP)
货号
RM17623
免疫原
Recombinant Human AMH/MIS Protein
Leu25-Arg560
Accession #Q6GTN3
纯化方式
Affinity purification
同种型
Rabbit IgG
内毒素水平
< 1.0 EU/μg of the protein by LAL method.
存储溶液
Supplied as a 0.2um filtered solution in PBS with 0.1%Braveds MB-1,PH 7.4.
CrossReactivity
No significant cross-reactivity was observed
存储条件
Store at -20℃. Avoid freeze / thaw cycles. Preservative:0.05%ProClin 300.Avoid repeated freeze-thaw cycles.

* This package insert must be read in its entirety before using this product.

应用

Human AMH/MIS Sandwich Immunoassay

 Recommended
Concentration
Sample
ELISA Capture1-4ug/mLRabbit anti-Human AMH/MIS mAb(CAP)(Cat. No. RM17623)
ELISA Detection0.1-0.4ug/mLHuman AMH/MIS Monoclonal Antibody, Rabbit MAb(DET)(Cat. No. RM17624)
Standard78-5000pg/mLRecombinant Human AMH Protein with His tag(Cat. No. RM00045)

背景信息

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome.

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